3-Bromo-1-phenylpiperidin-2-one

Base Information

Chemical Name:3-Bromo-1-phenylpiperidin-2-one
CAS No.:77868-85-0
Molecular Formula:C₁₁H₁₂BrNO
Molecular Weight:254.126
Hs Code.:
European Community (EC) Number:867-559-8
DSSTox Substance ID:DTXSID901304058

Synonyms:3-bromo-1-phenylpiperidin-2-one;77868-85-0;SCHEMBL22481526;3-Bromo-1-phenyl-2-piperidinone;DTXSID901304058;CDA86885;2-bromo-N-phenyl-delta-valerolactam;AKOS013434280;EN300-77429

Suppliers and Price of 3-Bromo-1-phenylpiperidin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 3-Bromo-1-phenylpiperidin-2-one

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:253.01023
Heavy Atom Count:14
Complexity:213

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CC(C(=O)N(C1)C2=CC=CC=C2)Br

Technology Process of 3-Bromo-1-phenylpiperidin-2-one

There total 6 articles about 3-Bromo-1-phenylpiperidin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 77868-78-1
2,5-Dibromo-pentanoic acid phenylamide

: 77868-85-0
3-bromo-1-phenylpiperidin-2-one

Guidance literature:: With sodium hydroxide; Duolite A-109; In dichloromethane; for 5.5h; Ambient temperature;
DOI:10.1246/cl.1981.185

Reference yield:

: 41339-29-1
2,5-Dibromo-pentanoyl chloride

: 77868-85-0
3-bromo-1-phenylpiperidin-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: Et₃N / CH₂Cl₂

2: Dowex 2x 10, 50percent aq. NaOH / CH₂Cl₂ / Ambient temperature

With sodium hydroxide; Dowex 2x 10; triethylamine; In dichloromethane;
DOI:10.1021/jm950886v

Reference yield:

: 62-53-3
aniline

: 77868-85-0
3-bromo-1-phenylpiperidin-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: Et₃N / CH₂Cl₂

2: Dowex 2x 10, 50percent aq. NaOH / CH₂Cl₂ / Ambient temperature

With sodium hydroxide; Dowex 2x 10; triethylamine; In dichloromethane;
DOI:10.1021/jm950886v