5''-(3-Bromo-propyl)-5-(3-{4-[tris-(4-tert-butyl-phenyl)-methyl]-phenoxy}-propyl)-[2,2';6',2'']terpyridine

Base Information

• Chemical Name: 5''-(3-Bromo-propyl)-5-(3-{4-[tris-(4-tert-butyl-phenyl)-methyl]-phenoxy}-propyl)-[2,2';6',2'']terpyridine
• CAS No.: 190366-44-0
• Molecular Formula: C₅₈H₆₄BrN₃O
• Molecular Weight: 899.07
• Mol file: 190366-44-0.mol

Synonyms:5''-(3-Bromo-propyl)-5-(3-{4-[tris-(4-tert-butyl-phenyl)-methyl]-phenoxy}-propyl)-[2,2';6',2'']terpyridine

Chemical Property of 5''-(3-Bromo-propyl)-5-(3-{4-[tris-(4-tert-butyl-phenyl)-methyl]-phenoxy}-propyl)-[2,2';6',2'']terpyridine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5''-(3-Bromo-propyl)-5-(3-{4-[tris-(4-tert-butyl-phenyl)-methyl]-phenoxy}-propyl)-[2,2';6',2'']terpyridine

There total 6 articles about 5''-(3-Bromo-propyl)-5-(3-{4-[tris-(4-tert-butyl-phenyl)-methyl]-phenoxy}-propyl)-[2,2';6',2'']terpyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

Methanesulfonic acid 3-[5''-(3-{4-[tris-(4-tert-butyl-phenyl)-methyl]-phenoxy}-propyl)-[2,2';6',2'']terpyridin-5-yl]-propyl ester (224784-40-1) → 5''-(3-Bromo-propyl)-5-(3-{4-[tris-(4-tert-butyl-phenyl)-methyl]-phenoxy}-propyl)-[2,2';6',2'']terpyridine (190366-44-0)

Guidance literature:

With lithium bromide; In acetone; Heating;

DOI:10.1016/S0040-4039(97)00678-3

Reference yield:

5,5''-dimethyl-2,2':6',2''-terpyridine (158589-14-1) → 5''-(3-Bromo-propyl)-5-(3-{4-[tris-(4-tert-butyl-phenyl)-methyl]-phenoxy}-propyl)-[2,2';6',2'']terpyridine (190366-44-0)

Guidance literature:

Multi-step reaction with 5 steps

1: 1.) LDA / 1.) THF, a) -78 deg C, 2 h, b) 0 deg C, 0.5 h, 2.) THF, from 0 deg C to RT, 16 h

2: 96 percent / aq. HCl, EtOH / 3 h / Heating

3: 90 percent / Et₃N / CH₂Cl₂ / 4 h / -2 °C

4: 13 percent / K₂CO₃ / dimethylformamide / 18 h / 75 °C

5: 80 percent / LiBr / acetone / 2 h / Heating

With hydrogenchloride; ethanol; potassium carbonate; triethylamine; lithium bromide; lithium diisopropyl amide; In dichloromethane; N,N-dimethyl-formamide; acetone;

DOI:10.1021/ja984051w

Reference yield:

5,5''-bis-(3-methanesulfonyl-1-propyl)-2,2':6',2''-terpyridine (158589-18-5) → 5''-(3-Bromo-propyl)-5-(3-{4-[tris-(4-tert-butyl-phenyl)-methyl]-phenoxy}-propyl)-[2,2';6',2'']terpyridine (190366-44-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 13 percent / K₂CO₃ / dimethylformamide / 18 h / 75 °C

2: 80 percent / LiBr / acetone / 2 h / Heating

With potassium carbonate; lithium bromide; In N,N-dimethyl-formamide; acetone;

DOI:10.1021/ja984051w

upstream raw materials:

Methanesulfonic acid 3-[5''-(3-{4-[tris-(4-tert-butyl-phenyl)-methyl]-phenoxy}-propyl)-[2,2';6',2'']terpyridin-5-yl]-propyl ester

5,5''-dimethyl-2,2':6',2''-terpyridine

5,5''-bis-(3-hydroxy-1-propyl)-2,2':6',2''-terpyridine

5,5''-bis-<3-<(tetrahydro-2H-pyran-2-yl)oxy>-1-propyl>-2,2':6',2''-terpyridine

Downstream raw materials:

5''-{4-[9-(4-Methoxy-phenyl)-[1,10]phenanthrolin-2-yl]-butyl}-5-(3-{4-[tris-(4-tert-butyl-phenyl)-methyl]-phenoxy}-propyl)-[2,2';6',2'']terpyridine