ethyl 3-phenyl-3-formylpropanoate

Base Information

• Chemical Name: ethyl 3-phenyl-3-formylpropanoate
• CAS No.: 2016-01-5
• Molecular Formula: C₁₂H₁₄O₃
• Molecular Weight: 206.241
• Mol file: 2016-01-5.mol

Synonyms:ethyl 3-phenyl-3-formylpropanoate

Chemical Property of ethyl 3-phenyl-3-formylpropanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl 3-phenyl-3-formylpropanoate

There total 8 articles about ethyl 3-phenyl-3-formylpropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

(E)-3-phenylhex-4-enoic acid ethyl ester (105576-28-1) → ethyl 3-phenyl-3-formylpropanoate (2016-01-5)

Guidance literature:

With ozone; In methanol; dichloromethane; at -78 ℃;

Reference yield: 49.0%

4-Methylsulfanyl-3-phenyl-4-(toluene-4-sulfonyl)-butyric acid ethyl ester (99764-03-1) → ethyl 3-phenyl-3-formylpropanoate (2016-01-5)

Guidance literature:

With sodium hydrogencarbonate; In 1,4-dioxane; water; for 1h; Irradiation;

DOI:10.1021/jo00354a020

Reference yield: 47.0%

diazoacetic acid ethyl ester (623-73-4) + phenylacetaldehyde (122-78-1) → ethyl 3-phenyl-3-formylpropanoate (2016-01-5)

Guidance literature:

With morpholine; lithium tetrafluoroborate; 5,15,10,20-tetraphenylporphyrin; In dimethyl sulfoxide; at 39 ℃; for 5h; pH=4; chemoselective reaction; Irradiation;

DOI:10.1021/jacs.6b09036

upstream raw materials:

4-oxo-3-phenyl-crotonic acid ethyl ester

4-Methylsulfanyl-3-phenyl-4-(toluene-4-sulfonyl)-butyric acid ethyl ester

(E)-3-phenylhex-4-enoic acid ethyl ester

ethyl (E)-1-phenylbut-1-en-3-ol

Downstream raw materials:

4-phenyl-5H-furan-2-one