(1R)-1-phenylethyl (3R)-4-{[{[3,5-bis(trifluoromethyl)phenyl]-methyl}(methyl)amino]carbonyl}-3-(4-fluoro-2-methylphenyl)-1-piperazinecarboxylate

Base Information

Chemical Name:(1R)-1-phenylethyl (3R)-4-{[{[3,5-bis(trifluoromethyl)phenyl]-methyl}(methyl)amino]carbonyl}-3-(4-fluoro-2-methylphenyl)-1-piperazinecarboxylate
CAS No.:334477-16-6
Molecular Formula:C₃₁H₃₀F₇N₃O₃
Molecular Weight:625.586
Hs Code.:

Synonyms:(1R)-1-phenylethyl (3R)-4-{[{[3,5-bis(trifluoromethyl)phenyl]-methyl}(methyl)amino]carbonyl}-3-(4-fluoro-2-methylphenyl)-1-piperazinecarboxylate

Suppliers and Price of (1R)-1-phenylethyl (3R)-4-{[{[3,5-bis(trifluoromethyl)phenyl]-methyl}(methyl)amino]carbonyl}-3-(4-fluoro-2-methylphenyl)-1-piperazinecarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (1R)-1-phenylethyl (3R)-4-{[{[3,5-bis(trifluoromethyl)phenyl]-methyl}(methyl)amino]carbonyl}-3-(4-fluoro-2-methylphenyl)-1-piperazinecarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (1R)-1-phenylethyl (3R)-4-{[{[3,5-bis(trifluoromethyl)phenyl]-methyl}(methyl)amino]carbonyl}-3-(4-fluoro-2-methylphenyl)-1-piperazinecarboxylate

There total 1 articles about (1R)-1-phenylethyl (3R)-4-{[{[3,5-bis(trifluoromethyl)phenyl]-methyl}(methyl)amino]carbonyl}-3-(4-fluoro-2-methylphenyl)-1-piperazinecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₂₂H₂₂Cl₃FN₂O₄

: N-[3,5-bis(trifluoromethyl)benzyl]methylamine hydrochloride

: 334477-70-2
(1R)-1-phenylethyl (3S)-4-{[{[3,5-bis(trifluoromethyl)phenyl]-methyl}(methyl)amino]carbonyl}-3-(4-fluoro-2-methylphenyl)-1-piperazinecarboxylate

: 334477-16-6
(1R)-1-phenylethyl (3R)-4-{[{[3,5-bis(trifluoromethyl)phenyl]-methyl}(methyl)amino]carbonyl}-3-(4-fluoro-2-methylphenyl)-1-piperazinecarboxylate

Guidance literature:: In dichloromethane; at 0 - 20 ℃;
DOI:10.1021/jm900023b

Reference yield: 61.0%

: 334477-16-6
(1R)-1-phenylethyl (3R)-4-{[{[3,5-bis(trifluoromethyl)phenyl]-methyl}(methyl)amino]carbonyl}-3-(4-fluoro-2-methylphenyl)-1-piperazinecarboxylate

: 334476-35-6
(2R)-N-{[3,5-bis(trifluoromethyl)phenyl]-methyl}-2-(4-fluoro-2-methylphenyl)-N-methyl-1-piperazinecarboxamide hydrochloride

Guidance literature:: (1R)-1-phenylethyl (3R)-4-{[{[3,5-bis(trifluoromethyl)phenyl]-methyl}(methyl)amino]carbonyl}-3-(4-fluoro-2-methylphenyl)-1-piperazinecarboxylate; With 5% Pd(II)/C(eggshell); hydrogen; In ethanol; water; for 4h; under 760.051 Torr;

With hydrogenchloride; In diethyl ether; ethanol; water;
DOI:10.1021/jm900023b