[2-(benzyloxy)but-3-yn-2-yl]benzene

Base Information

• Chemical Name: [2-(benzyloxy)but-3-yn-2-yl]benzene
• CAS No.: 129083-31-4
• Molecular Formula: C₁₇H₁₆O
• Molecular Weight: 236.313
• Mol file: 129083-31-4.mol

Synonyms:[2-(benzyloxy)but-3-yn-2-yl]benzene

Chemical Property of [2-(benzyloxy)but-3-yn-2-yl]benzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [2-(benzyloxy)but-3-yn-2-yl]benzene

There total 3 articles about [2-(benzyloxy)but-3-yn-2-yl]benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

2-Phenyl-3-butyn-2-ol (127-66-2) + benzyl alcohol (100-51-6,185532-71-2) → [2-(benzyloxy)but-3-yn-2-yl]benzene (129083-31-4)

Guidance literature:

With ferrocenium hexafluorophosphate; In dichloromethane; at 40 ℃; for 18h; Reagent/catalyst; Sealed tube;

DOI:10.1016/j.molcata.2015.06.009

Reference yield: 80.0%

2-Phenyl-3-butyn-2-ol (127-66-2) + benzyl alcohol (100-51-6,185532-71-2) → but-1-en-3-yn-2-ylbenzene (13120-47-3) + [2-(benzyloxy)but-3-yn-2-yl]benzene (129083-31-4)

Guidance literature:

With sodium hexaflorophosphate; (η5-indenyl)ruthenium(bis(triphenylphosphine))chloride; In toluene; acetonitrile; at 80 ℃; for 4h; Schlenk technique; Inert atmosphere;

DOI:10.1016/j.jorganchem.2017.03.043

Reference yield: 61.0%

2-Phenyl-3-butyn-2-ol (127-66-2) + benzyl bromide (100-39-0) → [2-(benzyloxy)but-3-yn-2-yl]benzene (129083-31-4)

Guidance literature:

2-Phenyl-3-butyn-2-ol; With sodium hydride; In tetrahydrofuran; mineral oil; at 20 ℃; for 1h; Inert atmosphere; Schlenk technique;

benzyl bromide; With tetra-(n-butyl)ammonium iodide; In tetrahydrofuran; mineral oil; at 50 ℃; Inert atmosphere; Schlenk technique;

DOI:10.1002/anie.201306843

upstream raw materials:

2-Phenyl-3-butyn-2-ol

benzyl bromide

benzyl alcohol

Downstream raw materials:

2-phenyl-2-benzyloxybutane

C₁₇H₁₈O