Opt_.-inakt. 4-Hydroxy-6.7-dimethoxy-2.3-dimethyl-1-(3.4-dimethoxy-phenyl)-1.2.3.4-tetrahydro-naphthalin

Base Information

• Chemical Name: Opt_.-inakt. 4-Hydroxy-6.7-dimethoxy-2.3-dimethyl-1-(3.4-dimethoxy-phenyl)-1.2.3.4-tetrahydro-naphthalin
• CAS No.: 111162-84-6
• Molecular Formula: C₂₂H₂₈O₅
• Molecular Weight: 372.461
• Mol file: 111162-84-6.mol

Synonyms:Opt_.-inakt. 4-Hydroxy-6.7-dimethoxy-2.3-dimethyl-1-(3.4-dimethoxy-phenyl)-1.2.3.4-tetrahydro-naphthalin

Chemical Property of Opt_.-inakt. 4-Hydroxy-6.7-dimethoxy-2.3-dimethyl-1-(3.4-dimethoxy-phenyl)-1.2.3.4-tetrahydro-naphthalin

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Opt_.-inakt. 4-Hydroxy-6.7-dimethoxy-2.3-dimethyl-1-(3.4-dimethoxy-phenyl)-1.2.3.4-tetrahydro-naphthalin

There total 5 articles about Opt_.-inakt. 4-Hydroxy-6.7-dimethoxy-2.3-dimethyl-1-(3.4-dimethoxy-phenyl)-1.2.3.4-tetrahydro-naphthalin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

C22H26O5 → Opt.-inakt. 4-Hydroxy-6.7-dimethoxy-2.3-dimethyl-1-(3.4-dimethoxy-phenyl)-1.2.3.4-tetrahydro-naphthalin (111162-84-6)

Guidance literature:

With sodium tetrahydroborate; In methanol; Cooling with ice;

DOI:10.1016/j.phytol.2015.06.001

Reference yield:

(7'R,8R,8'S)-8,8'-dimethyl-3',4',4,5-tetramethoxy-2,7'-cyclolignan-7-one (117404-44-1) → (7S,7'R,8R,8'S)-3',4',4,5-tetramethoxy-2,7'-cyclolignan-7-ol (6399-15-1,111162-84-6)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; for 0.5h;

DOI:10.1016/j.phytochem.2006.02.007

Reference yield:

1,4-bis-(3,4-dimethoxy-phenyl)-2,3-dimethyl-butane-1,4-diol (103239-13-0) → Opt.-inakt. 4-Hydroxy-6.7-dimethoxy-2.3-dimethyl-1-(3.4-dimethoxy-phenyl)-1.2.3.4-tetrahydro-naphthalin (111162-84-6)

Guidance literature:

With hydrogenchloride; Kochen des Reaktionsprodukts mit wss.-methanol. NaOH;

DOI:10.1039/jr9380001681

upstream raw materials:

(7'R,8R,8'S)-8,8'-dimethyl-3',4',4,5-tetramethoxy-2,7'-cyclolignan-7-one

1,4-bis-(3,4-dimethoxy-phenyl)-2,3-dimethyl-butane-1,4-diol

acetic acid

Downstream raw materials:

1-(3,4-dimethoxy-phenyl)-6,7-dimethoxy-2,3-dimethyl-naphthalene

(7'R,8'S)-3',4',4,5-tetramethoxy-2,7'-cyclolignan-7-ene

(7'S,8'R)-3',4',4,5-tetramethoxy-2,7'-cyclolignan-7-ene