diethyl 2-amino-2-[N-(1-benzyl-5-nitroimidazolyl-4-carbonyl)amino]malonate

Base Information

Chemical Name:diethyl 2-amino-2-[N-(1-benzyl-5-nitroimidazolyl-4-carbonyl)amino]malonate
CAS No.:1268388-57-3
Molecular Formula:C₁₈H₂₁N₅O₇
Molecular Weight:419.394
Hs Code.:

Synonyms:diethyl 2-amino-2-[N-(1-benzyl-5-nitroimidazolyl-4-carbonyl)amino]malonate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of diethyl 2-amino-2-[N-(1-benzyl-5-nitroimidazolyl-4-carbonyl)amino]malonate

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Technology Process of diethyl 2-amino-2-[N-(1-benzyl-5-nitroimidazolyl-4-carbonyl)amino]malonate

There total 1 articles about diethyl 2-amino-2-[N-(1-benzyl-5-nitroimidazolyl-4-carbonyl)amino]malonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1027264-94-3
2-[(1-Benzyl-5-nitro-1H-imidazole-4-carbonyl)-amino]-2-bromo-malonic acid diethyl ester

: 1268388-57-3
diethyl 2-amino-2-[N-(1-benzyl-5-nitroimidazolyl-4-carbonyl)amino]malonate

Guidance literature:: With ammonia; In tetrahydrofuran; acetone; for 1h;
DOI:10.1016/j.bmcl.2010.11.109

Reference yield: 83.0%

: 1268388-57-3
diethyl 2-amino-2-[N-(1-benzyl-5-nitroimidazolyl-4-carbonyl)amino]malonate

: 501-53-1,94274-21-2
benzyl chloroformate

: 1268388-58-4
diethyl 2-(benzyloxycarbonyl)amino-2-[N-(1-benzyl-5-nitroimidazolyl-4-carbonyl)amino]malonate

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; at 20 ℃; Inert atmosphere; Cooling with ice;
DOI:10.1016/j.bmcl.2010.11.109