6,8-dimethyl-2-({(2S)-1-[(2-methyl-5-phenyl-1,3-thiazol-4-yl)carbonyl]-2-piperidinyl}methyl)imidazo[1,2-α]pyrazine

Base Information

Chemical Name:6,8-dimethyl-2-({(2S)-1-[(2-methyl-5-phenyl-1,3-thiazol-4-yl)carbonyl]-2-piperidinyl}methyl)imidazo[1,2-α]pyrazine
CAS No.:1227852-62-1
Molecular Formula:C₂₅H₂₇N₅OS
Molecular Weight:445.588
Hs Code.:

Synonyms:6,8-dimethyl-2-({(2S)-1-[(2-methyl-5-phenyl-1,3-thiazol-4-yl)carbonyl]-2-piperidinyl}methyl)imidazo[1,2-α]pyrazine

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Chemical Property of 6,8-dimethyl-2-({(2S)-1-[(2-methyl-5-phenyl-1,3-thiazol-4-yl)carbonyl]-2-piperidinyl}methyl)imidazo[1,2-α]pyrazine

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Technology Process of 6,8-dimethyl-2-({(2S)-1-[(2-methyl-5-phenyl-1,3-thiazol-4-yl)carbonyl]-2-piperidinyl}methyl)imidazo[1,2-α]pyrazine

There total 2 articles about 6,8-dimethyl-2-({(2S)-1-[(2-methyl-5-phenyl-1,3-thiazol-4-yl)carbonyl]-2-piperidinyl}methyl)imidazo[1,2-α]pyrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 20.0%

: 91678-81-8
2-amino-3,5-dimethyl pyrazine

: 1097180-24-9
1,1-dimethylethyl (2S)-2-(3-bromo-2-oxopropyl)-1-piperidinecarboxylate

: 13743-09-4
2-methyl-5-phenyl-1,3-thiazole-4-carboxylic acid

: 1227852-62-1
6,8-dimethyl-2-({(2S)-1-[(2-methyl-5-phenyl-1,3-thiazol-4-yl)carbonyl]-2-piperidinyl}methyl)imidazo[1,2-α]pyrazine

Guidance literature:: 2-amino-3,5-dimethyl pyrazine; 1,1-dimethylethyl (2S)-2-(3-bromo-2-oxopropyl)-1-piperidinecarboxylate; In N,N-dimethyl-formamide; at 150 ℃; for 0.5h;

2-methyl-5-phenyl-1,3-thiazole-4-carboxylic acid; With oxalyl dichloride; triethylamine; In dichloromethane; N,N-dimethyl-formamide; at 0 - 20 ℃; for 1h;