N₃,N₅-bis((R)-2-hydroxy-1-phenylethyl)-4-phenyl-1H-pyrazole-3,5-dicarboxamide

Base Information

Chemical Name:N₃,N₅-bis((R)-2-hydroxy-1-phenylethyl)-4-phenyl-1H-pyrazole-3,5-dicarboxamide
CAS No.:1207950-66-0
Molecular Formula:C₂₇H₂₆N₄O₄
Molecular Weight:470.528
Hs Code.:

N<sub>3</sub>,N<sub>5</sub>-bis((R)-2-hydroxy-1-phenylethyl)-4-phenyl-1H-pyrazole-3,5-dicarboxamide

Synonyms:N₃,N₅-bis((R)-2-hydroxy-1-phenylethyl)-4-phenyl-1H-pyrazole-3,5-dicarboxamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N₃,N₅-bis((R)-2-hydroxy-1-phenylethyl)-4-phenyl-1H-pyrazole-3,5-dicarboxamide

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Technology Process of N₃,N₅-bis((R)-2-hydroxy-1-phenylethyl)-4-phenyl-1H-pyrazole-3,5-dicarboxamide

There total 1 articles about N₃,N₅-bis((R)-2-hydroxy-1-phenylethyl)-4-phenyl-1H-pyrazole-3,5-dicarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 56613-80-0
D-2-phenylglycinol

: 93041-20-4
4-phenyl-1H-pyrazole-3,5-dicarboxylic acid dimethyl ester

: 1207950-66-0
N₃,N₅-bis((R)-2-hydroxy-1-phenylethyl)-4-phenyl-1H-pyrazole-3,5-dicarboxamide

Guidance literature:: With potassium cyanide; In methanol; for 96h; Reflux;
DOI:10.1021/om900835f

Reference yield: 80.0%

: 1207950-66-0
N₃,N₅-bis((R)-2-hydroxy-1-phenylethyl)-4-phenyl-1H-pyrazole-3,5-dicarboxamide

: 3,5-bis((R)-4-phenyl-4,5-dihydro-2-oxazolyl)-1H-4-phenylpyrazole

Guidance literature:: N₃,N₅-bis((R)-2-hydroxy-1-phenylethyl)-4-phenyl-1H-pyrazole-3,5-dicarboxamide; With thionyl chloride; In 1,2-dichloro-ethane; at 40 ℃; for 2h;

With sodium methylate; In methanol; for 5h; Reflux;
DOI:10.1021/om900835f