1,3,5-tris(3-bromopropyl-N-methylamino)-2,4,6-dimethylaminobenzene

Base Information

• Chemical Name: 1,3,5-tris(3-bromopropyl-N-methylamino)-2,4,6-dimethylaminobenzene
• CAS No.: 189999-84-6
• Molecular Formula: C₂₄H₄₅Br₃N₆
• Molecular Weight: 657.374
• Mol file: 189999-84-6.mol

Synonyms:1,3,5-tris(3-bromopropyl-N-methylamino)-2,4,6-dimethylaminobenzene

Chemical Property of 1,3,5-tris(3-bromopropyl-N-methylamino)-2,4,6-dimethylaminobenzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,3,5-tris(3-bromopropyl-N-methylamino)-2,4,6-dimethylaminobenzene

There total 2 articles about 1,3,5-tris(3-bromopropyl-N-methylamino)-2,4,6-dimethylaminobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

1,3,5-tris(3-hydroxypropyl)methylamino-2,4,6-dimethylaminobenzene (189999-83-5) → 1,3,5-tris(3-bromopropyl-N-methylamino)-2,4,6-dimethylaminobenzene (189999-84-6)

Guidance literature:

With carbon tetrabromide; triphenylphosphine; In dichloromethane;

DOI:10.1002/anie.199706211

Reference yield:

Carbonic acid ethyl ester 3-(methyl-{2,4,6-tris-dimethylamino-3,5-bis-[(3-ethoxycarbonyloxy-propyl)-methyl-amino]-phenyl}-amino)-propyl ester → 1,3,5-tris(3-bromopropyl-N-methylamino)-2,4,6-dimethylaminobenzene (189999-84-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 4.27 g / 20percent KOH / ethanol / 0.08 h / Heating

2: 83 percent / CBr₄; PPh₃ / tetrahydrofuran / 20 °C

With carbon tetrabromide; triphenylphosphine; In tetrahydrofuran; ethanol;

DOI:10.1021/jo005744+

Reference yield: 91.0%

sodium cyanide (143-33-9,25596-52-5) + 1,3,5-tris(3-bromopropyl-N-methylamino)-2,4,6-dimethylaminobenzene (189999-84-6) → 1,3,5-tris(3-cyanopropyl-N-methylamino)-2,4,6-dimethylaminobenzene (189999-85-7)

Guidance literature:

In dimethyl sulfoxide; for 3h;

DOI:10.1021/jo005744+

upstream raw materials:

1,3,5-tris(3-hydroxypropyl)methylamino-2,4,6-dimethylaminobenzene

Downstream raw materials:

1,3,5-tris(3-cyanopropyl-N-methylamino)-2,4,6-dimethylaminobenzene

1,3,5-tris(4-aminobutyl-N-methylamino)-2,4,6-dimethylaminobenzene