1,3,5-tris(4-aminobutyl-N-methylamino)-2,4,6-dimethylaminobenzene

Base Information

• Chemical Name: 1,3,5-tris(4-aminobutyl-N-methylamino)-2,4,6-dimethylaminobenzene
• CAS No.: 189999-86-8
• Molecular Formula: C₂₇H₅₇N₉
• Molecular Weight: 507.81
• Mol file: 189999-86-8.mol

Synonyms:1,3,5-tris(4-aminobutyl-N-methylamino)-2,4,6-dimethylaminobenzene

Chemical Property of 1,3,5-tris(4-aminobutyl-N-methylamino)-2,4,6-dimethylaminobenzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,3,5-tris(4-aminobutyl-N-methylamino)-2,4,6-dimethylaminobenzene

There total 4 articles about 1,3,5-tris(4-aminobutyl-N-methylamino)-2,4,6-dimethylaminobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

1,3,5-tris(3-cyanopropyl-N-methylamino)-2,4,6-dimethylaminobenzene (189999-85-7) → 1,3,5-tris(4-aminobutyl-N-methylamino)-2,4,6-dimethylaminobenzene (189999-86-8)

Guidance literature:

With boron trifluoride-tetrahydrofuran complex;

DOI:10.1002/anie.199706211

Reference yield:

1,3,5-tris(3-hydroxypropyl)methylamino-2,4,6-dimethylaminobenzene (189999-83-5) → 1,3,5-tris(4-aminobutyl-N-methylamino)-2,4,6-dimethylaminobenzene (189999-86-8)

Guidance literature:

Multi-step reaction with 3 steps

1: 83 percent / CBr₄; PPh₃ / tetrahydrofuran / 20 °C

2: 91 percent / dimethylsulfoxide / 3 h

3: 80 percent / BH₃*THF / tetrahydrofuran / 3 h / Heating

With borane-THF; carbon tetrabromide; triphenylphosphine; In tetrahydrofuran; dimethyl sulfoxide;

DOI:10.1021/jo005744+

Reference yield:

1,3,5-tris(3-bromopropyl-N-methylamino)-2,4,6-dimethylaminobenzene (189999-84-6) → 1,3,5-tris(4-aminobutyl-N-methylamino)-2,4,6-dimethylaminobenzene (189999-86-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 91 percent / dimethylsulfoxide / 3 h

2: 80 percent / BH₃*THF / tetrahydrofuran / 3 h / Heating

With borane-THF; In tetrahydrofuran; dimethyl sulfoxide;

DOI:10.1021/jo005744+

upstream raw materials:

1,3,5-tris(3-cyanopropyl-N-methylamino)-2,4,6-dimethylaminobenzene

1,3,5-tris(3-hydroxypropyl)methylamino-2,4,6-dimethylaminobenzene

1,3,5-tris(3-bromopropyl-N-methylamino)-2,4,6-dimethylaminobenzene