(E)-hept-1-en-1-yldiphenylphosphine oxide

Base Information

• Chemical Name: (E)-hept-1-en-1-yldiphenylphosphine oxide
• CAS No.: 100585-48-6
• Molecular Formula: C₁₉H₂₃OP
• Molecular Weight: 298.365
• Mol file: 100585-48-6.mol

Synonyms:(E)-hept-1-en-1-yldiphenylphosphine oxide

Chemical Property of (E)-hept-1-en-1-yldiphenylphosphine oxide

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of (E)-hept-1-en-1-yldiphenylphosphine oxide

There total 5 articles about (E)-hept-1-en-1-yldiphenylphosphine oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 30.0%

oct-2-ynoic acid (5663-96-7) + Diphenylphosphine oxide (4559-70-0) → (E)-hept-1-en-1-yldiphenylphosphine oxide (100585-48-6)

Guidance literature:

With copper(l) chloride; In N,N-dimethyl-formamide; at 90 ℃; for 6h; stereoselective reaction; Inert atmosphere;

DOI:10.1021/ol502009b

Reference yield:

1-Heptyne (628-71-7) + Diphenylphosphine oxide (4559-70-0) → cis-(1-heptenyl)diphenylphosphine oxide (100632-10-8) + (E)-hept-1-en-1-yldiphenylphosphine oxide (100585-48-6)

Guidance literature:

With Eosin Y; potassium carbonate; In water; for 24h; Overall yield = 47 %; diastereoselective reaction; Irradiation; Inert atmosphere;

DOI:10.1021/acscatal.8b02617

Reference yield:

diphenyl((trimethylsilyl)methyl)phosphine oxide (4920-02-9) + hexanal (66-25-1) → cis-(1-heptenyl)diphenylphosphine oxide (100632-10-8) + (E)-hept-1-en-1-yldiphenylphosphine oxide (100585-48-6)

Guidance literature:

With n-butyllithium; Yield given. Multistep reaction. Yields of byproduct given; 1) THF, -78 deg C, 2) -78 deg C;

upstream raw materials:

diphenyl((trimethylsilyl)methyl)phosphine oxide

hexanal

1-Heptyne

Diphenylphosphine oxide