4920-02-9

Basic information

• Product Name: Phosphine oxide, diphenyl[(trimethylsilyl)methyl]-
• CAS NO: 4920-02-9
• Molecular Formula: C16H21OPSi
• Molecular Weight: 288.401
• Mol File: 4920-02-9.mol

Chemical Properties

• CAS DataBase Reference: Phosphine oxide, diphenyl[(trimethylsilyl)methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphine oxide, diphenyl[(trimethylsilyl)methyl]-(4920-02-9)
• EPA Substance Registry System: Phosphine oxide, diphenyl[(trimethylsilyl)methyl]-(4920-02-9)

Safety Data

• Hazardous Substances Data: 4920-02-9(Hazardous Substances Data)

Upstream product

• 1499-21-4 Diphenylphosphinic chloride 
• 75-77-4 chloro-trimethyl-silane 
• 2129-89-7 diphenyl(methyl)phosphine oxide 
• 719-80-2 Ethyl diphenylphosphinite 
• 2344-80-1 Chloromethyltrimethylsilane 

Downstream Products

• 78375-72-1 3-diphenylphosphinoylpentane-1,5-diol 
• 889-57-6 3-(diphenylphosphinoyl)-1-propanol 
• 87762-97-8 2-Benzyl-2-(diphenyl-phosphinoyl)-4,5-dimethyl-3,6-dihydro-2H-thiopyran 1-oxide 
• 87762-96-7 2-(Diphenyl-phosphinoyl)-2,4,5-trimethyl-3,6-dihydro-2H-thiopyran 1-oxide 
• 87763-23-3 1-(Methylsulfinyl)-1-(diphenylphosphoryl)-2-phenylethene 
• 87762-83-2 C₂₀H₁₇O₂PS 
• 87762-82-1 C₁₄H₁₃O₂PS 
• 148003-78-5 2-propyl(diphenyl)phosphine oxide 

Relevant articles and documents

The lithiation reactivity and selectivity of differentially branched alkyldiphenylphosphine oxides - A simple and versatile approach to ortho-functionalized arylphosphine oxides

Alkyldiphenylphosphine oxides typically undergo α-deprotonation with alkyllithium reagents. Here, the lithiation of differentially branched alkyldiphenylphosphine oxides was investigated and a diverse, but predictable reactivity was found. γ-Branched deri

Synthesis of phosphane oxides and phosphonates by cerium-mediated addition of organolithium compounds to chloro-phosphorus compounds

The addition of organocerium reagents 2a-g to phosphinoyl chloride 1a or chlorophosphates 1b leads to the synthesis of phosphane oxides 3aa-ag and phosphonates 3bb, be in good to high yield. The reaction can be extended to cerium enolates 4 (of ketones) and 6 (of nitriles) except when a benzyl group bound to the carbonyl moiety should be metallated. The latter reaction is the first reported synthesis of β-oxophosphane oxides by a simple reaction between enolates and a phosphorus(V) halide.

The Reactions of Tris(trimethylsilyl)methyl-lithium with Some Carbon Electrophiles

Tris(trimethylsilyl)methyl-lithium (1) reacts with non-enolisable aldehydes, ketones, and acid chlorides, and with some epoxides, with the formation of carbon-carbon bonds.This method of preparing functionalized silanes is limited by the readiness with which (1) abstracts a proton, if one is available, rather than attack at carbon.In the reaction with epoxides, the product alkoxide can transfer a silyl group from carbon to oxygen, and in one case the intermediate so formed reacts to give a cyclopropane (32) in what is a homologue of the Peterson reaction.The 1,4-transfer of a silyl group occurs in other systems when the resulting carbanion is stabilised by such groups as phenylthio and diphenylphosphinoyl.