4-(4-carboxypiperidin-1-yl)-2-(3-hydroxymethylphenyl)-6-morpholinopyrimidine

Base Information

Chemical Name:4-(4-carboxypiperidin-1-yl)-2-(3-hydroxymethylphenyl)-6-morpholinopyrimidine
CAS No.:941292-36-0
Molecular Formula:C₂₁H₂₆N₄O₄
Molecular Weight:398.462
Hs Code.:

Synonyms:4-(4-carboxypiperidin-1-yl)-2-(3-hydroxymethylphenyl)-6-morpholinopyrimidine

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Chemical Property of 4-(4-carboxypiperidin-1-yl)-2-(3-hydroxymethylphenyl)-6-morpholinopyrimidine

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Technology Process of 4-(4-carboxypiperidin-1-yl)-2-(3-hydroxymethylphenyl)-6-morpholinopyrimidine

There total 1 articles about 4-(4-carboxypiperidin-1-yl)-2-(3-hydroxymethylphenyl)-6-morpholinopyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 941292-37-1
2-(3-hydroxymethylphenyl)-4-(4-methoxycarbonylpiperidin-1-yl)-6-morpholinopyrimidine

: 941292-36-0
4-(4-carboxypiperidin-1-yl)-2-(3-hydroxymethylphenyl)-6-morpholinopyrimidine

Guidance literature:: 2-(3-hydroxymethylphenyl)-4-(4-methoxycarbonylpiperidin-1-yl)-6-morpholinopyrimidine; With sodium hydroxide; water; In 1,4-dioxane; at 20 ℃; for 18h;

With hydrogenchloride; In 1,4-dioxane; water;

Reference yield:

: 3731-53-1
4-(aminomethyl)pyridine

: 941292-36-0
4-(4-carboxypiperidin-1-yl)-2-(3-hydroxymethylphenyl)-6-morpholinopyrimidine

: 2-(3-hydroxymethylphenyl)-6-morpholino-4-[4-(N-pyridin-4-ylmethylcarbamoyl)piperidin-1-yl]pyrimidine

Guidance literature:: With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In ISOPROPYLAMIDE; at 20 ℃; for 3h;