Decahydroquinolin-6-ol

Base Information

• Chemical Name: Decahydroquinolin-6-ol
• CAS No.: 16878-29-8
• Molecular Formula: C₉H₁₇NO
• Molecular Weight: 155.24
• European Community (EC) Number: 845-240-4
• NSC Number: 137559
• Mol file: 16878-29-8.mol

Synonyms:decahydroquinolin-6-ol;16878-29-8;1,2,3,4,4a,5,6,7,8,8a-decahydroquinolin-6-ol;NSC137559;SCHEMBL9278083;NSC-137559;CS-0202308;EN300-247235

Chemical Property of Decahydroquinolin-6-ol

Chemical Property:

• XLogP3: 0.8
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 155.131014166
• Heavy Atom Count: 11
• Complexity: 138

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1CC2CC(CCC2NC1)O

Technology Process of Decahydroquinolin-6-ol

There total 1 articles about Decahydroquinolin-6-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ (+/-)-(4ar,8at)-decahydro-quinolin-6t-ol (16878-28-7,16878-29-8) + (+/-)-(4ar,8at)-decahydro-quinolin-7c-ol (1810-81-7,1971-16-0,16878-25-4,64474-32-4,64474-34-6,85551-08-2,90949-78-3)

Guidance literature:

With sodium borate; isopropyl alcohol;

DOI:10.1002/hlca.19650480416

Reference yield: 77.2%

6-hydroxy-1,2,3,4,4a,5,6,7,8,8a-decahydroquinoline (16878-29-8) + benzoyl chloride (98-88-4) → 1-benzoyl-6-hydroxy-1,2,3,4,4a,5,6,7,8,8a-decahydroquinoline (16878-38-9)

Guidance literature:

With potassium carbonate; In benzene; at 37 ℃; for 24h;

Reference yield:

6-hydroxy-1,2,3,4,4a,5,6,7,8,8a-decahydroquinoline (16878-29-8) → trans-1-benzoyl-1,2,3,4,4a,5,11,11a-octahydro-6H-pyrido<3,2-b>carbazole (133308-80-2,133565-07-8)

Guidance literature:

Multi-step reaction with 3 steps

1: 77.2 percent / K₂CO₃ / benzene / 24 h / 37 °C

2: 43 percent / CrO₃, H₂SO₄ / 1.) 0-2 deg C, 30 min, 2.) 25-30 deg C, 1 h

3: concd. HCl / ethanol / 4 h / Heating

With chromium(VI) oxide; hydrogenchloride; sulfuric acid; potassium carbonate; In ethanol; benzene;

Downstream raw materials:

1-benzoyl-6-hydroxy-1,2,3,4,4a,5,6,7,8,8a-decahydroquinoline

cis-4-benzoyl-1,2,3,4,4a,5,6,12b-octahydropyrido<2,3-c>acridine

trans-1-benzoyl-2,3,4,4a,5,7,8,8a-octahydro-6(1H)-quinolone

cis-1-benzoyl-2,3,4,4a,5,7,8,8a-octahydro-6(1H)-quinolone