7-amino-8-benzylaminoquinoline

Base Information

• Chemical Name: 7-amino-8-benzylaminoquinoline
• CAS No.: 120286-70-6
• Molecular Formula: C₁₆H₁₅N₃
• Molecular Weight: 249.315
• Mol file: 120286-70-6.mol

Synonyms:7-amino-8-benzylaminoquinoline

Chemical Property of 7-amino-8-benzylaminoquinoline

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of 7-amino-8-benzylaminoquinoline

There total 4 articles about 7-amino-8-benzylaminoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

8-benzylamino-7-nitroquinoline (120286-86-4) → 7-amino-8-benzylaminoquinoline (120286-70-6)

Guidance literature:

With iron; In acetic acid; for 1h; Ambient temperature;

DOI:10.1016/S0022-1139(00)81550-X

Reference yield: 53.0%

benzylamine (100-46-9) + 8-azidoquinoline (50400-06-1) → 7-amino-8-benzylaminoquinoline (120286-70-6)

Guidance literature:

In 1,4-dioxane; Irradiation;

DOI:10.1016/S0022-1139(00)81550-X

Reference yield:

2-chloro-3-nitroaniline (3970-41-0) → 7-amino-8-benzylaminoquinoline (120286-70-6)

Guidance literature:

Multi-step reaction with 3 steps

1: 65 percent / arsenic pentoxide, sulphuric acid / 4 h / 135 °C

2: 92 percent / ethanol / 6 h / Heating

3: 72 percent / iron powder / acetic acid / 1 h / Ambient temperature

With arsenic(V) oxide; sulfuric acid; iron; In ethanol; acetic acid;

DOI:10.1016/S0022-1139(00)81550-X

upstream raw materials:

8-benzylamino-7-nitroquinoline

benzylamine

8-azidoquinoline

2-chloro-3-nitroaniline