(4-((4-((5-chloro-1-phenylsulfonyl-1H-indol-2-yl)-sulfonyl)-2-oxopiperazin-1-yl)-methyl)-phenyl)-boronic acid

Base Information

Chemical Name:(4-((4-((5-chloro-1-phenylsulfonyl-1H-indol-2-yl)-sulfonyl)-2-oxopiperazin-1-yl)-methyl)-phenyl)-boronic acid
CAS No.:919110-21-7
Molecular Formula:C₂₅H₂₃BClN₃O₇S₂
Molecular Weight:587.87
Hs Code.:

Synonyms:(4-((4-((5-chloro-1-phenylsulfonyl-1H-indol-2-yl)-sulfonyl)-2-oxopiperazin-1-yl)-methyl)-phenyl)-boronic acid

Suppliers and Price of (4-((4-((5-chloro-1-phenylsulfonyl-1H-indol-2-yl)-sulfonyl)-2-oxopiperazin-1-yl)-methyl)-phenyl)-boronic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (4-((4-((5-chloro-1-phenylsulfonyl-1H-indol-2-yl)-sulfonyl)-2-oxopiperazin-1-yl)-methyl)-phenyl)-boronic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (4-((4-((5-chloro-1-phenylsulfonyl-1H-indol-2-yl)-sulfonyl)-2-oxopiperazin-1-yl)-methyl)-phenyl)-boronic acid

There total 2 articles about (4-((4-((5-chloro-1-phenylsulfonyl-1H-indol-2-yl)-sulfonyl)-2-oxopiperazin-1-yl)-methyl)-phenyl)-boronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 33.0%

: 249292-35-1
5-chloro-1-phenyl-sulfonylindole-2-sulfonyl chloride

: 919110-20-6
(4-(2-oxopiperazin-1-ylmethyl)-phenyl)boronic acid hydrochloride

: 919110-21-7
(4-((4-((5-chloro-1-phenylsulfonyl-1H-indol-2-yl)-sulfonyl)-2-oxopiperazin-1-yl)-methyl)-phenyl)-boronic acid

Guidance literature:: With triethylamine; In water; N,N-dimethyl-formamide; at 0 - 20 ℃; for 2h;

Reference yield:

: 919110-17-1
4-(4-iodobenzyl)-3-oxopiperazine-1-carboxylic acid tert-butyl ester

: 919110-21-7
(4-((4-((5-chloro-1-phenylsulfonyl-1H-indol-2-yl)-sulfonyl)-2-oxopiperazin-1-yl)-methyl)-phenyl)-boronic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: triethylamine / bis-triphenylphosphine-palladium(II) chloride / 1,4-dioxane / 2 h / 100 °C

1.2: 0.5 h

2.1: triethylamine / water; N,N-dimethyl-formamide / 2 h / 0 - 20 °C

With triethylamine; bis-triphenylphosphine-palladium(II) chloride; In 1,4-dioxane; water; N,N-dimethyl-formamide;

Reference yield: 53.0%

: 919110-21-7
(4-((4-((5-chloro-1-phenylsulfonyl-1H-indol-2-yl)-sulfonyl)-2-oxopiperazin-1-yl)-methyl)-phenyl)-boronic acid

: 919110-25-1
N-((5-chloro-1H-indol-2-yl)-sulfonyl)-N-(2-((4-dihydroxyborylbenzyl)amino)ethyl)glycine

Guidance literature:: (4-((4-((5-chloro-1-phenylsulfonyl-1H-indol-2-yl)-sulfonyl)-2-oxopiperazin-1-yl)-methyl)-phenyl)-boronic acid; With sodium hydroxide; In water; at 80 ℃; for 0.333333h;

In water;