6,7-dimethoxy-1-[2-(4-trifluormethylphenyl)ethyl]-3,4-dihydroisoquinoline

Base Information

Chemical Name:6,7-dimethoxy-1-[2-(4-trifluormethylphenyl)ethyl]-3,4-dihydroisoquinoline
CAS No.:1314227-83-2
Molecular Formula:C₂₀H₂₀F₃NO₂*H₂O₄S
Molecular Weight:461.459
Hs Code.:

Synonyms:6,7-dimethoxy-1-[2-(4-trifluormethylphenyl)ethyl]-3,4-dihydroisoquinoline

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Chemical Property of 6,7-dimethoxy-1-[2-(4-trifluormethylphenyl)ethyl]-3,4-dihydroisoquinoline

Chemical Property:

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Technology Process of 6,7-dimethoxy-1-[2-(4-trifluormethylphenyl)ethyl]-3,4-dihydroisoquinoline

There total 3 articles about 6,7-dimethoxy-1-[2-(4-trifluormethylphenyl)ethyl]-3,4-dihydroisoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 1314227-72-9
1-[2-(2-acetamidoethyl)-4,5-dimethoxyphenyl]-3-(4-trimethylphenyl)-1-propanone

: 1314227-83-2
6,7-dimethoxy-1-[2-(4-trifluormethylphenyl)ethyl]-3,4-dihydroisoquinoline

Guidance literature:: With sulfuric acid; In ethanol; at 60 ℃; Reflux;

Reference yield:

: 6275-29-2
N-[2-(3,4-dimethoxyphenyl)ethyl]acetamide

: 1314227-83-2
6,7-dimethoxy-1-[2-(4-trifluormethylphenyl)ethyl]-3,4-dihydroisoquinoline

Guidance literature:: Multi-step reaction with 2 steps

1: aluminum (III) chloride / nitrobenzene / 0 - 35 °C

2: sulfuric acid / ethanol / 60 °C / Reflux

With aluminum (III) chloride; sulfuric acid; In ethanol; nitrobenzene;

Reference yield:

: 539855-79-3
3-<4-(trifluoromethyl)phenyl>propanoyl chloride

: 1314227-83-2
6,7-dimethoxy-1-[2-(4-trifluormethylphenyl)ethyl]-3,4-dihydroisoquinoline

Guidance literature:: Multi-step reaction with 2 steps

1: aluminum (III) chloride / nitrobenzene / 0 - 35 °C

2: sulfuric acid / ethanol / 60 °C / Reflux

With aluminum (III) chloride; sulfuric acid; In ethanol; nitrobenzene;