3-(3,4-Dihydroxyphenyl)-6,7-dihydroxy-4H-chromen-4-one

Base Information

Chemical Name:3-(3,4-Dihydroxyphenyl)-6,7-dihydroxy-4H-chromen-4-one
CAS No.:109588-95-6
Molecular Formula:C₁₅H₁₀O₆
Molecular Weight:286.241
Hs Code.:
NSC Number:678115
DSSTox Substance ID:DTXSID001341601
Nikkaji Number:J705.765B

Synonyms:6,7,3',4'-tetrahydroxyisoflavone

Suppliers and Price of 3-(3,4-Dihydroxyphenyl)-6,7-dihydroxy-4H-chromen-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-(3,4-Dihydroxyphenyl)-6,7-dihydroxy-4H-chromen-4-one

Chemical Property:

XLogP3:1.8
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:1
Exact Mass:286.04773803
Heavy Atom Count:21
Complexity:447

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=C(C=C1C2=COC3=CC(=C(C=C3C2=O)O)O)O)O

Technology Process of 3-(3,4-Dihydroxyphenyl)-6,7-dihydroxy-4H-chromen-4-one

There total 4 articles about 3-(3,4-Dihydroxyphenyl)-6,7-dihydroxy-4H-chromen-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 24126-93-0
6,7-dimethoxy-3-(3,4-dimethoxyphenyl)-4H-chromen-4-one

: 109588-95-6
6,7,3',4'-tetrahydroxyisoflavone

Guidance literature:: With aluminum (III) chloride; dimethylsulfide; In dichloromethane; at 10 - 30 ℃; for 12h; Large scale;
DOI:10.1080/00397911.2014.886331

Reference yield:

: 2033-89-8
3,4-dimethoxyphenol

: 109588-95-6
6,7,3',4'-tetrahydroxyisoflavone

Guidance literature:: Multi-step reaction with 3 steps

1.1: hydrogenchloride; zinc(II) chloride / 1,4-dioxane / 6 h / 20 °C / Large scale

1.2: 24 h / 20 °C / Large scale

1.3: 1 h / 85 °C / Large scale

2.1: boron trifluoride diethyl etherate / N,N-dimethyl-formamide / 3 h / 0 - 10 °C / Large scale

2.2: 8 h / 20 - 27 °C / Large scale

2.3: 2 h / 85 °C / Large scale

3.1: aluminum (III) chloride; dimethylsulfide / dichloromethane / 12 h / 10 - 30 °C / Large scale

With hydrogenchloride; aluminum (III) chloride; dimethylsulfide; boron trifluoride diethyl etherate; zinc(II) chloride; In 1,4-dioxane; dichloromethane; N,N-dimethyl-formamide; 1.1: |Houben-Hoesch Phenol Acylation / 1.2: |Houben-Hoesch Phenol Acylation / 1.3: |Houben-Hoesch Phenol Acylation / 2.1: |Vilsmeier-Haack Formylation / 2.2: |Vilsmeier-Haack Formylation / 2.3: |Vilsmeier-Haack Formylation;
DOI:10.1080/00397911.2014.886331

Reference yield:

: 93-17-4
3,4-dimethoxyphenylacetonitrile

: 109588-95-6
6,7,3',4'-tetrahydroxyisoflavone

Guidance literature:: Multi-step reaction with 3 steps

1.1: hydrogenchloride; zinc(II) chloride / 1,4-dioxane / 6 h / 20 °C / Large scale

1.2: 24 h / 20 °C / Large scale

1.3: 1 h / 85 °C / Large scale

2.1: boron trifluoride diethyl etherate / N,N-dimethyl-formamide / 3 h / 0 - 10 °C / Large scale

2.2: 8 h / 20 - 27 °C / Large scale

2.3: 2 h / 85 °C / Large scale

3.1: aluminum (III) chloride; dimethylsulfide / dichloromethane / 12 h / 10 - 30 °C / Large scale

With hydrogenchloride; aluminum (III) chloride; dimethylsulfide; boron trifluoride diethyl etherate; zinc(II) chloride; In 1,4-dioxane; dichloromethane; N,N-dimethyl-formamide; 1.1: |Houben-Hoesch Phenol Acylation / 1.2: |Houben-Hoesch Phenol Acylation / 1.3: |Houben-Hoesch Phenol Acylation / 2.1: |Vilsmeier-Haack Formylation / 2.2: |Vilsmeier-Haack Formylation / 2.3: |Vilsmeier-Haack Formylation;
DOI:10.1080/00397911.2014.886331