6,7,7a,8-Tetrahydro-7-methyl-5H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline

Base Information

Chemical Name:6,7,7a,8-Tetrahydro-7-methyl-5H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline
CAS No.:15548-23-9
Molecular Formula:C₁₈H₁₇NO₂
Molecular Weight:279.338
Hs Code.:
Mol file:15548-23-9.mol

Synonyms:(?à)-Roemerine; Aporphine,1,2-[methylenebis(oxy)]-

Suppliers and Price of 6,7,7a,8-Tetrahydro-7-methyl-5H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 6,7,7a,8-Tetrahydro-7-methyl-5H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline

Chemical Property:

Boiling Point:424.0±34.0 °C(Predicted)
PKA:7.87±0.20(Predicted)
PSA：0.00000
Density:1.269±0.06 g/cm3(Predicted)
LogP:0.00000

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 6,7,7a,8-Tetrahydro-7-methyl-5H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline

There total 11 articles about 6,7,7a,8-Tetrahydro-7-methyl-5H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: (S)-methyl 7a,8-dihydro-5H-[1,3]dioxolo[4',5':4,5]benzo[1,2,3-de]benzo[g]quinoline-7(6H)-carboxylate

: 548-08-3,2030-53-7,15548-23-9
(+)-roemerine

Guidance literature:: (S)-methyl 7a,8-dihydro-5H-[1,3]dioxolo[4',5':4,5]benzo[1,2,3-de]benzo[g]quinoline-7(6H)-carboxylate; With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 20 ℃; for 24h; Inert atmosphere;

With water; In tetrahydrofuran; at 20 ℃;
DOI:10.1039/c7md00629b

Reference yield:

: 3466-56-6
(+)-mecambroline

: 548-08-3,2030-53-7,15548-23-9
(+)-roemerine

Guidance literature:: Multi-step reaction with 2 steps

1: NaH / dimethylformamide

2: H₂ / Pd-C / acetic acid

With hydrogen; sodium hydride; palladium on activated charcoal; In acetic acid; N,N-dimethyl-formamide;