Technology Process of C41H51N2O8P
There total 7 articles about C41H51N2O8P which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 11.2 g / imidazole / dimethylformamide / Ambient temperature
2: 0.704 g / K2CO3 / benzene; diethyl ether; H2O
3: 40 percent / Bu4NF / tetrahydrofuran / 1 h
4: 65 percent / pyridine, 4-(dimethylamino)pyridine
5: 98 percent / Bu4NF / tetrahydrofuran / 3 h
6: 1.) imidazole, PCl3, Et3N, 2.) water / 1.) MeCN, 4 h, 2.) MeCN, 30 min
With
pyridine; 1H-imidazole; dmap; tetrabutyl ammonium fluoride; water; potassium carbonate; triethylamine; phosphorus trichloride;
In
tetrahydrofuran; diethyl ether; water; N,N-dimethyl-formamide; benzene;
DOI:10.1021/ja00049a003
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 65 percent / pyridine, 4-(dimethylamino)pyridine
2: 98 percent / Bu4NF / tetrahydrofuran / 3 h
3: 1.) imidazole, PCl3, Et3N, 2.) water / 1.) MeCN, 4 h, 2.) MeCN, 30 min
With
pyridine; 1H-imidazole; dmap; tetrabutyl ammonium fluoride; water; triethylamine; phosphorus trichloride;
In
tetrahydrofuran;
DOI:10.1021/ja00049a003
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 0.704 g / K2CO3 / benzene; diethyl ether; H2O
2: 40 percent / Bu4NF / tetrahydrofuran / 1 h
3: 65 percent / pyridine, 4-(dimethylamino)pyridine
4: 98 percent / Bu4NF / tetrahydrofuran / 3 h
5: 1.) imidazole, PCl3, Et3N, 2.) water / 1.) MeCN, 4 h, 2.) MeCN, 30 min
With
pyridine; 1H-imidazole; dmap; tetrabutyl ammonium fluoride; water; potassium carbonate; triethylamine; phosphorus trichloride;
In
tetrahydrofuran; diethyl ether; water; benzene;
DOI:10.1021/ja00049a003