124883-99-4

Upstream product

• 63945-11-9 6-phthalimido-1-hexanol 
• 4048-33-3 6-amino-1-hexanol 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 1581260-78-7 C₂₁H₃₆N₂O₃SSi 
• 135137-85-8 1-N-(4,4'-Dimethoxytrityl)-biotinyl-6-amino-1-tert-butyldimethylsilylhexan-1-ol 
• 135137-86-9 1-N-(4,4'-Dimethoxytrityl)-biotinyl-6-amino-hexan-1-ol 
• 144002-83-5 C₄₁H₅₁N₂O₈P 
• 144002-84-6 Diisopropyl-phosphoramidous acid 6-(4-{6-[bis-(4-methoxy-phenyl)-phenyl-methoxy]-hexylcarbamoyl}-benzoylamino)-hexyl ester 2-cyano-ethyl ester 
• 144002-79-9 N'-<6-(tert-butyldimethylsiloxy)hexyl>-N-<(6-(4,4'-dimethoxytrityl)oxy)hexyl>terephthalamide 
• 144002-82-4 N-<6-((4,4'-dimethoxytrityl)oxy)hexyl>-N'-(6-hydroxyhexyl)terephthalamide 
• 144002-78-8 N-<6-(tert-butyldimethylsiloxy)hexyl>-N'-(6-hydroxyhexyl)terephthalamide 
• 244214-16-2 5-(2-oxo-hexahydro-thieno[3,4-d]imidazol-6-yl)-pentanoic acid {2-[bis-(4-methoxy-phenyl)-phenyl-methoxy]-1-[6-(tert-butyl-dimethyl-silanyloxy)-hexylcarbamoyl]-ethyl}-amide 
• 144002-77-7 N,N'-bis<6-(tert-butyldimethylsiloxy)hexyl>terephthalamide 

Relevant academic research and scientific papers

Design, Synthesis and Characterization of Pyrimidine based Thiazolidinedione Derivatives

Novel thiazolidine-2,4-dione (TZD) based pyrimidine derivatives have been synthesized by Knoevenagel condensation reaction between thiazolidine-2,4-dione and amino pyrimidinyl aliphatic aldehydes followed by heterogeneous metal reduction. Synthetic strate

IMINOSUGARS USEFUL FOR THE TREATMENT OF VIRAL DISEASES

Formula IA, ad their use for treating viral infections.

PYRIDINE DERIVATIVES AND METHODS OF USE

The invention relates to compounds for use in the modification of compounds comprising nucleic acid sequences (such as oligonucleotides or the like), to modified oligonucleotides, to the delivery of modified oligonucleotides to cells and the like, and to the treatment of conditions by the delivery of modified oligonucleotides. The invention provides pyridine derived phosphoramidites, phosphorothioates, phosphate esters, solid supported equivalents, related oligonucleotides and the delivery of these to cells.

Control of folding and binding of oligonucleotides by use of a nonnucleotide linker

A linker containing a terephthalamide group, -P(O)(O-)O(CH2)6NHC(O)C6H 4C(O)NH(CH2)6OP(O)(O-)-, is shown to be an effective structural element for organizing oligonucl

A LONG CHAIN BIOTIN PHOSPHORAMIDITE REAGENT FOR THE AUTOMATED SYNTHESIS OF 5'-BIOTINYLATED OLIGONUCLEOTIDES

An N-dimethoxytritylated biotin group coupled to a 6-aminohexanol linker was converted into a phosphoramidite to yield a biotinylating reagent which can be used in automated solid-phase synthesis to produce 5'-biotinylated oligonucleotides in high yields.