2-Carbethoxy-1,2-dimethyl-1-p-tolylcyclopentane

Base Information

Chemical Name:2-Carbethoxy-1,2-dimethyl-1-p-tolylcyclopentane
CAS No.:51941-56-1
Molecular Formula:C₁₇H₂₄O₂
Molecular Weight:260.376
Hs Code.:

Synonyms:2-Carbethoxy-1,2-dimethyl-1-p-tolylcyclopentane

Suppliers and Price of 2-Carbethoxy-1,2-dimethyl-1-p-tolylcyclopentane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 2-Carbethoxy-1,2-dimethyl-1-p-tolylcyclopentane

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

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Technology Process of 2-Carbethoxy-1,2-dimethyl-1-p-tolylcyclopentane

There total 32 articles about 2-Carbethoxy-1,2-dimethyl-1-p-tolylcyclopentane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: ethyl cis-1,2-dimethyl-2-(4-methylphenyl)cyclopent-3-enecarboxylate

: 51941-56-1,100847-95-8,138573-11-2
ethyl cis-1,2-dimethyl-2-(4-methylphenyl)cyclopentanecarboxylate

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; at 20 ℃; for 1h; under 760.051 Torr;

Reference yield:

: 130633-06-6,148802-06-6,94853-54-0
(E)-3-(4-methylphenyl)-but-2-en-1-ol

: 51941-56-1,100847-95-8,138573-11-2
ethyl cis-1,2-dimethyl-2-(4-methylphenyl)cyclopentanecarboxylate

Guidance literature:: Multi-step reaction with 5 steps

1: 80 percent / propionic acid / 48 h / 180 °C

2: 88 percent / LDA / tetrahydrofuran / 4 h / -70 - 20 °C

3: 98 percent / Grubbs' catalyst / CH₂Cl₂ / 4 h / 20 °C

4: 82 percent / LDA / tetrahydrofuran; hexamethylphosphoric acid triamide / 8 h / 0 - 20 °C

5: H₂ / Pd/C / ethanol / 1 h / 20 °C / 760 Torr

With hydrogen; propionic acid; lithium diisopropyl amide; palladium on activated charcoal; Grubbs catalyst first generation; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; ethanol; dichloromethane; 1: orthoester Claisen rearragement;
DOI:10.1016/S0040-4039(01)02051-2

Reference yield:

: 140137-52-6
ethyl 3-methyl-3-(4-methylphenyl)-pent-4-enoate

: 51941-56-1,100847-95-8,138573-11-2
ethyl cis-1,2-dimethyl-2-(4-methylphenyl)cyclopentanecarboxylate

Guidance literature:: Multi-step reaction with 4 steps

1: 88 percent / LDA / tetrahydrofuran / 4 h / -70 - 20 °C

2: 98 percent / Grubbs' catalyst / CH₂Cl₂ / 4 h / 20 °C

3: 82 percent / LDA / tetrahydrofuran; hexamethylphosphoric acid triamide / 8 h / 0 - 20 °C

4: H₂ / Pd/C / ethanol / 1 h / 20 °C / 760 Torr

With hydrogen; lithium diisopropyl amide; palladium on activated charcoal; Grubbs catalyst first generation; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; ethanol; dichloromethane;
DOI:10.1016/S0040-4039(01)02051-2