1-(2-Methoxy-phenyl)-2,2-dimethyl-3-phenyl-propane-1,3-dione

Base Information

• Chemical Name: 1-(2-Methoxy-phenyl)-2,2-dimethyl-3-phenyl-propane-1,3-dione
• CAS No.: 126516-71-0
• Molecular Formula: C₁₈H₁₈O₃
• Molecular Weight: 282.339
• Mol file: 126516-71-0.mol

Synonyms:1-(2-Methoxy-phenyl)-2,2-dimethyl-3-phenyl-propane-1,3-dione

Chemical Property of 1-(2-Methoxy-phenyl)-2,2-dimethyl-3-phenyl-propane-1,3-dione

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 1-(2-Methoxy-phenyl)-2,2-dimethyl-3-phenyl-propane-1,3-dione

There total 1 articles about 1-(2-Methoxy-phenyl)-2,2-dimethyl-3-phenyl-propane-1,3-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(2-methoxyphenyl)-3-phenylpropane-1,3-dione (41126-22-1) + methyl iodide (74-88-4) → 1-(2-Methoxy-phenyl)-2,2-dimethyl-3-phenyl-propane-1,3-dione (126516-71-0)

Guidance literature:

Yield given. Multistep reaction;

DOI:10.1055/s-1989-27359

Reference yield: 78.0%

1-(2-Methoxy-phenyl)-2,2-dimethyl-3-phenyl-propane-1,3-dione (126516-71-0) → 3-(2'-methoxyphenyl)-4,4-dimethyl-5-phenyl-4H-pyrazole

Guidance literature:

With hydrazine hydrate; In chloroform; at 60 ℃; for 24h;

DOI:10.1039/a905773k

Reference yield:

1-(2-Methoxy-phenyl)-2,2-dimethyl-3-phenyl-propane-1,3-dione (126516-71-0) → (1a,4a,4aα,7aα)-4,4a,5,6,7,7a-hexahydro-1-(2'-methoxyphenyl)-8,8-dimethyl-4-phenyl-1,4-methano-1H-cyclopenta[d]pyridazine

Guidance literature:

Multi-step reaction with 2 steps

1: 78 percent / N₂H₄*H₂O / CHCl₃ / 24 h / 60 °C

2: 8 percent / toluene / 110 °C / 9375750 Torr

With hydrazine hydrate; In chloroform; toluene; 1: Cyclization / 2: Cycloaddition;

DOI:10.1039/a905773k

upstream raw materials:

1-(2-methoxyphenyl)-3-phenylpropane-1,3-dione

methyl iodide