methiodal sodium

Base Information

• Chemical Name: methiodal sodium
• CAS No.: 126-31-8
• Molecular Formula: CH3 I O3 S . Na
• Molecular Weight: 243.985
• Hs Code.: 2904909090
• Mol file: 126-31-8.mol

Synonyms:Methanesulfonicacid, iodo-, sodium salt (7CI,8CI,9CI); Methiodal sodium (6CI); Abrodan;Abrodil; Conturex; Diagnorenol; Iodomethanesulfonic acid sodium salt;Kontrast-U; Myelotrast; Neo-Sombraven; Radiographol; Sergosin; Sergozin;Skiodan; Sodium iodomethanesulfonate; Sodium methiodal; Sodiummonoiodomethanesulfonate

Chemical Property of methiodal sodium

Chemical Property:

• PSA: 62.75000
• LogP: 1.34750

Purity/Quality:

98%min ^*data from raw suppliers

Sodium iodomethanesulfonate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Radiopaque contrast medium.

Technology Process of methiodal sodium

There total 3 articles about methiodal sodium which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

diiodomethane (75-11-6) → sodium iodomethanesulfonate (126-31-8)

Guidance literature:

With tetra(n-butyl)ammonium hydrogensulfate; sodium sulfite; In ethanol; water; for 16h; Reflux;

DOI:10.1016/j.bmcl.2008.09.004

Reference yield:

diiodomethane (75-11-6) → sodium iodomethanesulfonate (126-31-8)

Guidance literature:

In water; Heating;

DOI:10.1021/jo00193a048

Reference yield:

iodoform (75-47-8) + sodium sulfite (7757-83-7) → sodium iodomethanesulfonate (126-31-8) + sodium hydrogensulfite

Guidance literature:

With water; byproducts: NaI, Na2SO4;

upstream raw materials:

diiodomethane

iodoform

sodium sulfite

Downstream raw materials:

(4-methoxy-phenoxy)-methanesulfonic acid

(2,4-dichloro-phenoxy)-methanesulfonic acid

p-tolyloxy-methanesulfonic acid

iodomethanesulfonyl chloride

Refernces

• 1、 Gao, Feng,Yan, Xuxu,Zahr, Omar,Larsen, Aaron,Vong, Kenward,Auclair, Karine. "Synthesis and use of sulfonamide-, sulfoxide-, or sulfone-containing aminoglycoside-CoA bisubstrates as mechanistic probes for aminoglycoside N-6′-acetyltransferase". supporting information; experimental part. p. 5518 - 5522. Retrieved 2009/05/30.