4,5-dihydroxyphthalic acid diethyl ester

Base Information

• Chemical Name: 4,5-dihydroxyphthalic acid diethyl ester
• CAS No.: 1006694-57-0
• Molecular Formula: C₁₂H₁₄O₆
• Molecular Weight: 254.24
• Mol file: 1006694-57-0.mol

Synonyms:4,5-dihydroxyphthalic acid diethyl ester

Chemical Property of 4,5-dihydroxyphthalic acid diethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4,5-dihydroxyphthalic acid diethyl ester

There total 3 articles about 4,5-dihydroxyphthalic acid diethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

diethyl (2R,3R)-2,3-dimethoxy-2,3-dimethyl-2,3-dihydro-1,4-benzodioxin-6,7-dicarboxylate → 4,5-dihydroxyphthalic acid diethyl ester (1006694-57-0)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; for 4h; Heating;

DOI:10.1016/j.tetlet.2007.11.085

Reference yield:

m-hemipinic acid (577-68-4) → 4,5-dihydroxyphthalic acid diethyl ester (1006694-57-0)

Guidance literature:

Multi-step reaction with 2 steps

1: hydriodic acid; phosphorus

2: hydrogen chloride

With hydrogenchloride; phosphorus; hydrogen iodide;

Reference yield:

ethanol (64-17-5) + 4,5-dihydroxyphthalic acid (63958-66-7) → 4,5-dihydroxyphthalic acid diethyl ester (1006694-57-0)

Guidance literature:

With hydrogenchloride;

upstream raw materials:

ethanol

4,5-dihydroxyphthalic acid

m-hemipinic acid