5'-O-adenosine

Base Information

Chemical Name:5'-O-adenosine
CAS No.:120673-70-3
Molecular Formula:C₂₀H₂₅N₆O₇P
Molecular Weight:492.428
Hs Code.:

5'-O-<hydroxy(4-phenyl-3-amino-2-oxobutyl)phosphinyl>adenosine

Synonyms:5'-O-adenosine

Suppliers and Price of 5'-O-adenosine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5'-O-adenosine

Chemical Property:

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Technology Process of 5'-O-adenosine

There total 7 articles about 5'-O-adenosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.7%

: 120649-93-6
N⁶-dimethylaminomethylene-5'-O-2,'3'-O-ethoxymethyleneadenosine

: 120673-70-3
5'-O-adenosine

Guidance literature:: α-chymotrypsin; In various solvent(s); at 25 ℃; for 6h; pH = 7.8;
DOI:10.1016/S0040-4020(01)89835-5

Reference yield:

: L-(4-phenyl-3-acetylamino-2-oxobutyl)phosphonic acid ethyl ester

: 120673-70-3
5'-O-adenosine

Guidance literature:: Multi-step reaction with 4 steps

1: 96.8 percent / alkaline phosphatase / various solvent(s) / 6 h / 37 °C / pH = 10.4

2: 59.3 percent / N,N'-dicyclohexylcarbodiimide / ethyl acetate / 48 h / Ambient temperature

3: 1.) phosphorus pentachloride 2.) ice / 1.) phosphorus pentachloride, tetrachlormethane, heating 2.) ice, 2 h

4: 35.7 percent / α-chymotrypsin / various solvent(s) / 6 h / 25 °C / pH = 7.8

With phosphorus pentachloride; Methamphetamin; dicyclohexyl-carbodiimide; α-chymotrypsin; alkaline phosphatase; In ethyl acetate;
DOI:10.1016/S0040-4020(01)89835-5

Reference yield:

: 120649-78-7
L-(4-phenyl-3-acetylamino-2-oxobutyl)phosphonic acid monoethyl ester

: 120673-70-3
5'-O-adenosine

Guidance literature:: Multi-step reaction with 3 steps

1: 59.3 percent / N,N'-dicyclohexylcarbodiimide / ethyl acetate / 48 h / Ambient temperature

2: 1.) phosphorus pentachloride 2.) ice / 1.) phosphorus pentachloride, tetrachlormethane, heating 2.) ice, 2 h

3: 35.7 percent / α-chymotrypsin / various solvent(s) / 6 h / 25 °C / pH = 7.8

With phosphorus pentachloride; Methamphetamin; dicyclohexyl-carbodiimide; α-chymotrypsin; In ethyl acetate;
DOI:10.1016/S0040-4020(01)89835-5