2-(9H-fluoren-9-ylidene)-3-(4-methoxyphenyl)-5-oxopyrazolidin-2-ium-1-ide

Base Information

• Chemical Name: 2-(9H-fluoren-9-ylidene)-3-(4-methoxyphenyl)-5-oxopyrazolidin-2-ium-1-ide
• CAS No.: 1401072-43-2
• Molecular Formula: C₂₃H₁₈N₂O₂
• Molecular Weight: 354.408
• Mol file: 1401072-43-2.mol

Synonyms:2-(9H-fluoren-9-ylidene)-3-(4-methoxyphenyl)-5-oxopyrazolidin-2-ium-1-ide

Chemical Property of 2-(9H-fluoren-9-ylidene)-3-(4-methoxyphenyl)-5-oxopyrazolidin-2-ium-1-ide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(9H-fluoren-9-ylidene)-3-(4-methoxyphenyl)-5-oxopyrazolidin-2-ium-1-ide

There total 3 articles about 2-(9H-fluoren-9-ylidene)-3-(4-methoxyphenyl)-5-oxopyrazolidin-2-ium-1-ide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

4-Methoxystyrene (637-69-4,24936-44-5) + phenyl 2-(9H-fluoren-9-ylidene)hydrazine-1-carboxylate (1401072-73-8) → 2-(9H-fluoren-9-ylidene)-3-(4-methoxyphenyl)-5-oxopyrazolidin-2-ium-1-ide (1401072-43-2)

Guidance literature:

at 100 ℃; for 3h; Inert atmosphere;

DOI:10.1021/acs.joc.6b02713

Reference yield: 74.0%

→ 2-(9H-fluoren-9-ylidene)-3-(4-methoxyphenyl)-5-oxopyrazolidin-2-ium-1-ide (1401072-43-2)

Guidance literature:

at 150 ℃; for 3h; Inert atmosphere; Microwave irradiation;

Reference yield:

9-fluorenone (486-25-9,952573-42-1) → 2-(9H-fluoren-9-ylidene)-3-(4-methoxyphenyl)-5-oxopyrazolidin-2-ium-1-ide (1401072-43-2)

Guidance literature:

Multi-step reaction with 2 steps

1: acetic acid / methanol / Reflux

2: 3 h / 100 °C / Microwave irradiation; Sealed tube

With acetic acid; In methanol;

DOI:10.1021/ja305491t

upstream raw materials:

4-Methoxystyrene

phenyl 2-(9H-fluoren-9-ylidene)hydrazine-1-carboxylate

9-fluorenone

Downstream raw materials:

3-((9H-fluoren-9-yl)amino)-3-(4-methoxyphenyl)propanamide