C₁₈H₃₀BN

Base Information

• Chemical Name: C₁₈H₃₀BN
• CAS No.: 1206604-44-5
• Molecular Formula: C₁₈H₃₀BN
• Molecular Weight: 271.254
• Mol file: 1206604-44-5.mol

Synonyms:C₁₈H₃₀BN

Chemical Property of C₁₈H₃₀BN

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of C₁₈H₃₀BN

There total 1 articles about C₁₈H₃₀BN which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-hexynonitrile (14918-21-9) + bis(cyclohexanyl)borane (1568-65-6) → C18H30BN (1206604-44-5)

Guidance literature:

With dimethyl sulfide borane; cyclohexene; In tetrahydrofuran; at 0 - 20 ℃; for 2.25h; regioselective reaction; Inert atmosphere;

DOI:10.1021/ol1023213

Reference yield: 74.0%

C18H30BN (1206604-44-5) + benzaldehyde (100-52-7) → (R,E)-7-hydroxy-7-phenylhept-5-enenitrile (1256289-18-5)

Guidance literature:

With titanium(IV) isopropylate; (R)-3-(3,5-diphenylphenyl)-2,2'-dihydroxy-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthyl; In tetrahydrofuran; at 20 ℃; optical yield given as %ee; enantioselective reaction; Inert atmosphere; Reflux;

DOI:10.1021/ol1023213

Reference yield: 63.0%

C18H30BN (1206604-44-5) + 4-methyl-benzaldehyde (104-87-0) → (R,E)-7-hydroxy-7-(p-tolyl)hept-5-enenitrile (1256289-20-9)

Guidance literature:

With titanium(IV) isopropylate; (R)-3-(3,5-diphenylphenyl)-2,2'-dihydroxy-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthyl; In tetrahydrofuran; at 20 ℃; optical yield given as %ee; enantioselective reaction; Inert atmosphere; Reflux;

DOI:10.1021/ol1023213

upstream raw materials:

5-hexynonitrile

bis(cyclohexanyl)borane

Downstream raw materials:

(R,E)-7-hydroxy-7-(p-tolyl)hept-5-enenitrile

(R,E)-7-hydroxy-7-phenylhept-5-enenitrile