Chemical Property of CID 9793764
Chemical Property:
- Vapor Pressure:0.000156mmHg at 25°C
- Melting Point:145-146
- Boiling Point:295.6°Cat760mmHg
- Flash Point:146.8°C
- PSA：57.53000
- Density:g/cm3
- LogP:-0.15650
- Storage Temp.:Controlled Substance, -20?C Freezer
- Hydrogen Bond Donor Count:2
- Hydrogen Bond Acceptor Count:3
- Rotatable Bond Count:3
- Exact Mass:127.03711339
- Heavy Atom Count:8
- Complexity:60
- Purity/Quality:
-
Safty Information:
- Pictogram(s):
F,T
- Hazard Codes:F,T
- Statements:
11-23/24/25-39/23/24/25
- Safety Statements:
22-24/25-45-36/37-16-7
- MSDS Files:
-
Useful:
- Canonical SMILES:C(CC(=O)O)CO.[Na]
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Description
Xyrem is distributed by Jazz Pharmaceuticals, Inc. (Palo Alto,
CA). It is an oral solution of sodium oxybate prescribed for
narcoleptic patients to treat extreme daytime sleepiness and
cataplexy. Xyrem is also known as sodium oxybate which is the
same as gamma hydroxybutyric acid (GHB), a drug of abuse.
GHB is endogenously produced and present in the central
nervous system (CNS) in small concentrations. Accidental
overdosing has led to many hospitalizations and deaths.
Because of the tendency to abuse GHB, it was classified as
a schedule I controlled substance. This meant that GHB had
a high potential for abuse and no medical purpose. However,
in 2002, because of a series of clinical trials that demonstrated
that the compound reduces cataplexy attacks, it was approved
for use under the trademark Xyrem. Since GHB had previously
been used as a ‘date-rape’ drug, Xyrem is considered a schedule
III controlled substance and is distributed in accordance with
strict FDA regulations. Xyrem may only be ordered through the
‘Xyrem Success Program.’ Illegal use is punishable under
federal and state laws. GHB (sodium salt) (exempt preparation) (Item No. 15661) is an analytical reference standard categorized as a CNS depressant. GHB is a metabolite of γ-butyrolactone . It has a high potential for abuse. GHB is regulated as a Schedule I compound in the United States. GHB (sodium salt) (exempt preparation) (Item No. 15661) is provided as a DEA exempt preparation. This product is intended for research and forensic applications.
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Uses
4-Hydroxybutyric acid sodium salt is an agonist to both GHB and GABAB neural receptors, exhibiting neurotransmitter-like effects. It has been used as a general anesthetic in treatment for sleep disorders and clinical depression, but also has been identified as a “date rape drug”. antibacterial Xyrem is used as a prescription drug for the treatment of
cataplexy in patients with narcolepsy. It can also be used illegally
for recreational purposes as well as drug-facilitated sexual
assault.
This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.
