2-(bromomethyl)phenyl phenylacetate

Base Information

• Chemical Name: 2-(bromomethyl)phenyl phenylacetate
• CAS No.: 1301768-66-0
• Molecular Formula: C₁₅H₁₃BrO₂
• Molecular Weight: 305.171
• Mol file: 1301768-66-0.mol

Synonyms:2-(bromomethyl)phenyl phenylacetate

Chemical Property of 2-(bromomethyl)phenyl phenylacetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(bromomethyl)phenyl phenylacetate

There total 3 articles about 2-(bromomethyl)phenyl phenylacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

2-methylphenyl phenylacetate (2491-29-4) → 2-(bromomethyl)phenyl phenylacetate (1301768-66-0)

Guidance literature:

With N-Bromosuccinimide; In tetrachloromethane; for 1h; UV-irradiation;

DOI:10.1016/j.tetlet.2011.02.070

Reference yield:

ortho-cresol (95-48-7,77504-84-8) → 2-(bromomethyl)phenyl phenylacetate (1301768-66-0)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine / 0 °C

2: N-Bromosuccinimide / tetrachloromethane / Irradiation

With pyridine; N-Bromosuccinimide; In tetrachloromethane;

DOI:10.1016/j.tetlet.2010.12.104

Reference yield:

phenylacetic acid (103-82-2) → 2-(bromomethyl)phenyl phenylacetate (1301768-66-0)

Guidance literature:

Multi-step reaction with 2 steps

1: thionyl chloride

2: N-Bromosuccinimide / tetrachloromethane / 1 h / UV-irradiation

With N-Bromosuccinimide; thionyl chloride; In tetrachloromethane;

DOI:10.1016/j.tetlet.2011.02.070

upstream raw materials:

2-methylphenyl phenylacetate

ortho-cresol

phenylacetic acid

Downstream raw materials:

2-benzylbenzofuran

(2-phenylacetoxybenzyl)triphenylphosphonium bromide