hydroxymethyldicyclohexylphosphine

Base Information

• Chemical Name: hydroxymethyldicyclohexylphosphine
• CAS No.: 92031-76-0
• Molecular Formula: C₁₃H₂₅OP
• Molecular Weight: 228.315
• Mol file: 92031-76-0.mol

Synonyms:hydroxymethyldicyclohexylphosphine

Chemical Property of hydroxymethyldicyclohexylphosphine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of hydroxymethyldicyclohexylphosphine

There total 2 articles about hydroxymethyldicyclohexylphosphine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 22.0%

2-(N-methylamino)pyridine (4597-87-9) + dicyclohexyl-bis(hydroxymethyl)phosphonium chloride (58395-72-5) → C19H31N2P*BH3 + hydroxymethyldicyclohexylphosphine (92031-76-0)

Guidance literature:

dicyclohexyl-bis(hydroxymethyl)phosphonium chloride; With triethylamine; In methanol; for 2h; Heating;

2-(N-methylamino)pyridine; In methanol; Heating;

With dimethylsulfide borane complex; In diethyl ether; Further stages.;

DOI:10.1039/b709032c

Reference yield:

dicyclohexylphosphane (829-84-5) → hydroxymethyldicyclohexylphosphine (92031-76-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 98 percent / 36percent aq. HCl

2: Et₃N / methanol; H₂O

With hydrogenchloride; triethylamine; In methanol; water;

DOI:10.1039/DT9930002563

Reference yield: 96.0%

tert-butylamine (75-64-9) + hydroxymethyldicyclohexylphosphine (92031-76-0) → Cy2PCH2NHtBu (1234313-14-4)

Guidance literature:

In dichloromethane; at 20 ℃; Inert atmosphere;

DOI:10.1016/j.jorganchem.2010.03.006

upstream raw materials:

2-(N-methylamino)pyridine

dicyclohexyl-bis(hydroxymethyl)phosphonium chloride

dicyclohexylphosphane

Downstream raw materials:

Cy₂PCH₂NHtBu

Cy₂PCH₂NHPh

C₂₉H₅₅NP₂

C₃₀H₅₇NP₂