(2R,3R)-tert-butyl 3-(tert-butoxycarbonylamino)-3-(4-fluorophenyl)-2-methyl-2-nitro-propanoate

Base Information

Chemical Name:(2R,3R)-tert-butyl 3-(tert-butoxycarbonylamino)-3-(4-fluorophenyl)-2-methyl-2-nitro-propanoate
CAS No.:1010805-27-2
Molecular Formula:C₁₉H₂₇FN₂O₆
Molecular Weight:398.432
Hs Code.:

Synonyms:(2R,3R)-tert-butyl 3-(tert-butoxycarbonylamino)-3-(4-fluorophenyl)-2-methyl-2-nitro-propanoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2R,3R)-tert-butyl 3-(tert-butoxycarbonylamino)-3-(4-fluorophenyl)-2-methyl-2-nitro-propanoate

Chemical Property:

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Technology Process of (2R,3R)-tert-butyl 3-(tert-butoxycarbonylamino)-3-(4-fluorophenyl)-2-methyl-2-nitro-propanoate

There total 3 articles about (2R,3R)-tert-butyl 3-(tert-butoxycarbonylamino)-3-(4-fluorophenyl)-2-methyl-2-nitro-propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 18598-92-0
2-nitropropanoic acid tert-butyl ester

: 1010805-16-9
p-fluorobenzaldehyde N-(tert-butoxycarbonyl)imine

: C₁₉H₂₇FN₂O₆

: 1010805-27-2
(2R,3R)-tert-butyl 3-(tert-butoxycarbonylamino)-3-(4-fluorophenyl)-2-methyl-2-nitro-propanoate

: (2RS,3SR)-tert-butyl 3-(tert-butoxycarbonylamino)-3-(4-fluorophenyl)-2-methyl-2-nitro-propanoate

Guidance literature:: With 4 A molecular sieve; nickel complex of (R)-Schiff base, derivative of binaphthyl; In tetrahydrofuran; at 0 ℃; for 12h; Title compound not separated from byproducts.;
DOI:10.1021/ja710398q