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Usage

Uses

Used in Pharmaceutical Industry:
Propanoic acid, 2-nitro-, 1,1-dimethylethyl ester is used as an intermediate in the synthesis of various pharmaceuticals. Its chemical structure allows it to be a key component in the development of new drugs, contributing to the advancement of medicinal chemistry.
Used in Agrochemical Industry:
In the agrochemical sector, this ester derivative is utilized as an intermediate for the production of different agrochemicals. Its role in this industry is crucial for the development of effective and safe products for agricultural applications.
Used in Organic Compounds Synthesis:
Propanoic acid, 2-nitro-, 1,1-dimethylethyl ester is used as a building block in the synthesis of other organic compounds. Its versatility in chemical reactions makes it a valuable asset in the creation of a wide range of organic molecules for various purposes.
Used as a Solvent in Paints and Coatings Industry:
Propanoic acid, 2-nitro-, 1,1-dimethylethyl ester serves as a solvent in the manufacturing of paints and coatings. Its ability to dissolve and carry other components makes it an essential part of the formulation process, ensuring the quality and performance of the final product.
Used as a Preservative in the Food Industry:
Propanoic acid, 2-nitro-, 1,1-dimethylethyl ester is also used as a preservative in the food industry. Its properties help to extend the shelf life of food products, maintaining their freshness and quality.
It is important to handle Propanoic acid, 2-nitro-, 1,1-dimethylethyl ester with care, as it is considered hazardous to human health and the environment. Proper safety measures and disposal methods should be strictly followed to minimize any potential risks associated with its use.

Upstream product

• 39149-80-9 tert-butyl 2-bromopropionate 
• 20487-40-5 tert-butyl propionate 

Downstream Products

• 1373945-78-8 C₁₆H₂₅NO₂ 
• 1380419-54-4 (E)-tert-butyl 5-(benzyloxy)-2-methyl-2-nitrohepta-4,6-dienoate 
• 1380419-51-1 (4E,6E)-tert-butyl 2-methyl-2-nitro-7-phenylhepta-4,6-dienoate 
• 1380419-52-2 (4E,6E)-tert-butyl 7-(benzyldimethylsilyl)-2-methyl-2-nitrohepta-4,6-dienoate 
• 1010805-09-0 (2R,3R)-tert-butyl 3-(tert-butoxycarbonylamino)-2-methyl-2-nitro-3-phenylpropanoate 
• 1185743-61-6 C₃₇H₄₃NO₁₀P₂ 
• 1010805-23-8 (2R,3R)-tert-butyl 3-(tert-butoxycarbonylamino)-3-(4-methoxyphenyl)-2-methyl-2-nitro-propanoate 
• 1044200-49-8 C₂₀H₃₀N₂O₇ 
• 1010805-37-4 C₁₉H₂₈N₂O₆ 

Relevant academic research and scientific papers

Asymmetric Michael addition of α-nitro-ketones using catalytic peptides

Peptide-based catalysts have been developed that promote the asymmetric Michael addition of nitroalkanes. The most effective peptides contain a β-turn structural element as well as a basic histidine and an arylsulfonamide-protected arginine. Excellent yields with enantioselectivities of up to 74% ee have been observed.

Inclusion complexes of EMPO derivatives with 2,6-di-O-methyl-β- cyclodextrin: Synthesis, NMR and EPR investigations for enhanced superoxide detection

The free radical trapping properties of eight 5-alkoxycarbonyl-5-methyl-1- pyrroline N-oxide (EMPO) type nitrones and those of 5,5-dimethyl-1-pyrroline N-oxide (DMPO) were evaluated for trapping of superoxide anion radicals in the presence of 2,6-di-O-methyl-β-cyclodextrin (DM-β-CD). 1H-NMR titrations were performed to determine both stoichiometries and binding constants for the diamagnetic nitrone-DM-β-CD equilibria. EPR titrations were then performed and analyzed using a two-dimensional EPR simulation program affording 1: 1 and 1: 2 stoichiometries for the nitroxide spin adducts with DM-β-CD and the associated binding constants after spin trapping. The nitroxide spin adducts associate more strongly with DM-β-CD than the nitrones. The ability of the nitrones to trap superoxide, the enhancement of the EPR signal intensity and the supramolecular protection by DM-β-CD against sodium l-ascorbate reduction were evaluated. The Royal Society of Chemistry 2006.