Technology Process of 3,3a-dihydroxy-4,6-bis(benzyloxy)-2,3,3a,8a-tetrahydrofuro<2,3-b>benzofuran
There total 5 articles about 3,3a-dihydroxy-4,6-bis(benzyloxy)-2,3,3a,8a-tetrahydrofuro<2,3-b>benzofuran which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 42 percent / HBr / CH2Cl2 / 0.33 h / 25 °C
2: 1.) aq. oxalic acid, 2.) aq. sodium hydroxide / 1.) acetone, reflux, 0.5 h, 2.) tetrahydrofuran, 25 deg C, 23.5 h
With
sodium hydroxide; hydrogen bromide; oxalic acid;
In
dichloromethane;
DOI:10.1021/ja00402a039
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 55 percent / aq. potassium hydroxide / methanol; H2O / 0.5 h / Heating
2: potassium iodide, potassium carbonate / dimethylformamide / 12 h / 25 °C
3: 95 percent / aq. potassium hydroxide / methanol; H2O / 18 h / Heating
4: 42 percent / HBr / CH2Cl2 / 0.33 h / 25 °C
5: 1.) aq. oxalic acid, 2.) aq. sodium hydroxide / 1.) acetone, reflux, 0.5 h, 2.) tetrahydrofuran, 25 deg C, 23.5 h
With
potassium hydroxide; sodium hydroxide; hydrogen bromide; oxalic acid; potassium carbonate; potassium iodide;
In
methanol; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1021/ja00402a039
- Guidance literature:
-
Multi-step reaction with 4 steps
1: potassium iodide, potassium carbonate / dimethylformamide / 12 h / 25 °C
2: 95 percent / aq. potassium hydroxide / methanol; H2O / 18 h / Heating
3: 42 percent / HBr / CH2Cl2 / 0.33 h / 25 °C
4: 1.) aq. oxalic acid, 2.) aq. sodium hydroxide / 1.) acetone, reflux, 0.5 h, 2.) tetrahydrofuran, 25 deg C, 23.5 h
With
potassium hydroxide; sodium hydroxide; hydrogen bromide; oxalic acid; potassium carbonate; potassium iodide;
In
methanol; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1021/ja00402a039
