Technology Process of C18H20F2O2
There total 7 articles about C18H20F2O2 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
boron tribromide;
In
dichloromethane;
at -60 ℃;
for 0.5h;
DOI:10.1021/jm00371a004
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 51 percent / KMnO4 / pyridine; H2O / 2 h / 50 °C
2: SOCl2 / 4 h / Heating
3: 67 percent / diethyl ether; tetrahydrofuran / 1 h / -78 - 20 °C
4: 57 percent / Zn, TiCl4 / dioxane / 4 h / 101 °C
5: 89 percent / H2 / 10percent Pd/C / ethanol
6: 77 percent / BBr3 / CH2Cl2 / 0.5 h / -60 °C
With
potassium permanganate; thionyl chloride; hydrogen; boron tribromide; titanium tetrachloride; zinc;
palladium on activated charcoal;
In
tetrahydrofuran; 1,4-dioxane; pyridine; diethyl ether; ethanol; dichloromethane; water;
DOI:10.1021/jm00371a004
- Guidance literature:
-
Multi-step reaction with 5 steps
1: SOCl2 / 4 h / Heating
2: 67 percent / diethyl ether; tetrahydrofuran / 1 h / -78 - 20 °C
3: 57 percent / Zn, TiCl4 / dioxane / 4 h / 101 °C
4: 89 percent / H2 / 10percent Pd/C / ethanol
5: 77 percent / BBr3 / CH2Cl2 / 0.5 h / -60 °C
With
thionyl chloride; hydrogen; boron tribromide; titanium tetrachloride; zinc;
palladium on activated charcoal;
In
tetrahydrofuran; 1,4-dioxane; diethyl ether; ethanol; dichloromethane;
DOI:10.1021/jm00371a004
