4-[4-(5-cyclohexyl-2-methoxyphenyl)thiazol-2-ylcarbamoyl]piperazine-1-carboxylic acid tert-butylester

Base Information

Chemical Name:4-[4-(5-cyclohexyl-2-methoxyphenyl)thiazol-2-ylcarbamoyl]piperazine-1-carboxylic acid tert-butylester
CAS No.:944042-98-2
Molecular Formula:C₂₆H₃₆N₄O₄S
Molecular Weight:500.662
Hs Code.:

Synonyms:4-[4-(5-cyclohexyl-2-methoxyphenyl)thiazol-2-ylcarbamoyl]piperazine-1-carboxylic acid tert-butylester

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Chemical Property of 4-[4-(5-cyclohexyl-2-methoxyphenyl)thiazol-2-ylcarbamoyl]piperazine-1-carboxylic acid tert-butylester

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Technology Process of 4-[4-(5-cyclohexyl-2-methoxyphenyl)thiazol-2-ylcarbamoyl]piperazine-1-carboxylic acid tert-butylester

There total 1 articles about 4-[4-(5-cyclohexyl-2-methoxyphenyl)thiazol-2-ylcarbamoyl]piperazine-1-carboxylic acid tert-butylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 784177-17-9
4-(5-Cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-amine

: 1-((2,5-dioxo pyrrolidinyl)carbonyl)pyrrolidine-2,5-dione

: 57260-71-6
1-t-Butoxycarbonylpiperazine

: 944042-98-2
4-[4-(5-cyclohexyl-2-methoxyphenyl)thiazol-2-ylcarbamoyl]piperazine-1-carboxylic acid tert-butylester

Guidance literature:: 4-(5-Cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-amine; 1-((2,5-dioxo pyrrolidinyl)carbonyl)pyrrolidine-2,5-dione; In 1,1-dichloroethane; at 20 ℃; for 16h;

1-t-Butoxycarbonylpiperazine; In 1,1-dichloroethane; at 20 ℃; for 3h;

Reference yield:

: 944042-98-2
4-[4-(5-cyclohexyl-2-methoxyphenyl)thiazol-2-ylcarbamoyl]piperazine-1-carboxylic acid tert-butylester

: 944042-99-3
piperazine-1-carboxylic acid [4-(5-cyclohexyl-2-methoxyphenyl)thiazol-2-yl]amide

Guidance literature:: 4-[4-(5-cyclohexyl-2-methoxyphenyl)thiazol-2-ylcarbamoyl]piperazine-1-carboxylic acid tert-butylester; With hydrogenchloride; In 1,4-dioxane; at 20 ℃; for 4h;

With sodium hydroxide; In dichloromethane; water;