piperazine-1-carboxylic acid [4-(5-cyclohexyl-2-methoxyphenyl)thiazol-2-yl]amide

Base Information

Chemical Name:piperazine-1-carboxylic acid [4-(5-cyclohexyl-2-methoxyphenyl)thiazol-2-yl]amide
CAS No.:944042-99-3
Molecular Formula:C₂₁H₂₈N₄O₂S
Molecular Weight:400.545
Hs Code.:

Synonyms:piperazine-1-carboxylic acid [4-(5-cyclohexyl-2-methoxyphenyl)thiazol-2-yl]amide

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Chemical Property of piperazine-1-carboxylic acid [4-(5-cyclohexyl-2-methoxyphenyl)thiazol-2-yl]amide

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Technology Process of piperazine-1-carboxylic acid [4-(5-cyclohexyl-2-methoxyphenyl)thiazol-2-yl]amide

There total 1 articles about piperazine-1-carboxylic acid [4-(5-cyclohexyl-2-methoxyphenyl)thiazol-2-yl]amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 944042-98-2
4-[4-(5-cyclohexyl-2-methoxyphenyl)thiazol-2-ylcarbamoyl]piperazine-1-carboxylic acid tert-butylester

: 944042-99-3
piperazine-1-carboxylic acid [4-(5-cyclohexyl-2-methoxyphenyl)thiazol-2-yl]amide

Guidance literature:: 4-[4-(5-cyclohexyl-2-methoxyphenyl)thiazol-2-ylcarbamoyl]piperazine-1-carboxylic acid tert-butylester; With hydrogenchloride; In 1,4-dioxane; at 20 ℃; for 4h;

With sodium hydroxide; In dichloromethane; water;

Reference yield:

: 50675-18-8
3,4,5,6-tetrahydro-2H-pyran-4-carbaldehyde

: 944042-99-3
piperazine-1-carboxylic acid [4-(5-cyclohexyl-2-methoxyphenyl)thiazol-2-yl]amide

: 944043-01-0
4-(tetrahydropyran-4-ylmethyl)piperazine-1-carboxylic acid [4-(5-cyclohexyl-2-methoxyphenyl)thiazol-2-yl]amide

Guidance literature:: 3,4,5,6-tetrahydro-2H-pyran-4-carbaldehyde; piperazine-1-carboxylic acid [4-(5-cyclohexyl-2-methoxyphenyl)thiazol-2-yl]amide; In 1,1-dichloroethane; at 20 ℃; for 1h;

With sodium tris(acetoxy)borohydride; In 1,1-dichloroethane; at 20 ℃; for 12h;