1,4-Dibutyrylpiperazine

Base Information

• Chemical Name: 1,4-Dibutyrylpiperazine
• CAS No.: 17730-78-8
• Molecular Formula: C12H22N2O2
• Molecular Weight: 0
• Hs Code.: 2933599090
• Mol file: 17730-78-8.mol

Synonyms:Piperazine,1,4-dibutyryl;1,4-Dibutyrylpiperazine;

Chemical Property of 1,4-Dibutyrylpiperazine

Chemical Property:

• PSA: 40.62000
• LogP: 1.13320

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,4-Dibutyrylpiperazine

There total 3 articles about 1,4-Dibutyrylpiperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

piperazine (110-85-0) + butyryl chloride (141-75-3) → 1-(4-butanoylpiperazin-1-yl)butan-1-one (17730-78-8)

Guidance literature:

With triethylamine; In chloroform; at 20 ℃; for 0.0222222h; Flow reactor;

DOI:10.1002/chem.201501785

Reference yield: 56.0%

piperazine (110-85-0) + butyl butyrate (109-21-7) → 1-(4-butanoylpiperazin-1-yl)butan-1-one (17730-78-8)

Guidance literature:

With carbonylhydrido[6-(di-tert-butylphosphinomethylene)-2-(N,N-diethylaminomethyl)-1,6-dihydropyridine]ruthenium(II); In toluene; benzene; at 135 ℃; for 36h; Inert atmosphere;

DOI:10.1021/ja109944n

Reference yield:

→ 1-(4-butanoylpiperazin-1-yl)butan-1-one (17730-78-8)

Guidance literature:

Piperazin, Butyrylchlorid;

DOI:10.1021/jm00310a022

upstream raw materials:

piperazine

butyl butyrate

butyryl chloride