3-Benzoyl-4-hydroxy-4,5,5-trimethyl-2-oxazolidinone

Base Information

Chemical Name:3-Benzoyl-4-hydroxy-4,5,5-trimethyl-2-oxazolidinone
CAS No.:202920-25-0
Molecular Formula:C₁₃H₁₅NO₄
Molecular Weight:249.266
Hs Code.:
DSSTox Substance ID:DTXSID401222005

Synonyms:DTXSID401222005;3-Benzoyl-4-hydroxy-4,5,5-trimethyl-2-oxazolidinone;202920-25-0

Suppliers and Price of 3-Benzoyl-4-hydroxy-4,5,5-trimethyl-2-oxazolidinone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 3-Benzoyl-4-hydroxy-4,5,5-trimethyl-2-oxazolidinone

Chemical Property:

XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:249.10010796
Heavy Atom Count:18
Complexity:373

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1(C(N(C(=O)O1)C(=O)C2=CC=CC=C2)(C)O)C

Technology Process of 3-Benzoyl-4-hydroxy-4,5,5-trimethyl-2-oxazolidinone

There total 1 articles about 3-Benzoyl-4-hydroxy-4,5,5-trimethyl-2-oxazolidinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 4437-80-3
4,4-dimethyl-5-methylene-1,3-dioxolan-2-one

: 55-21-0,27208-38-4
benzamide

: 202920-25-0
N-benzoyl-4-hydroxy-4,5,5-trimethyl-1,3-oxazolidin-2-one

Guidance literature:: With sodium hydride; In tetrahydrofuran; dichloromethane; paraffin; for 4h; Ambient temperature;
DOI:10.1021/jo971733d

Reference yield:

: 202920-25-0
N-benzoyl-4-hydroxy-4,5,5-trimethyl-1,3-oxazolidin-2-one

: (S)-3-Benzoyl-4,5,5-trimethyl-oxazolidin-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: 26 percent / p-toluenesulfonic acid / toluene / 12 h / Heating

2: 85 percent / hydrogen, <((R)-(1,1'-binaphthyl-2,2'-diyl)bis(diphenylphosphine))RuCl₂>2NEt₃ / methanol / 18 h / 50 °C / 75006 Torr

With <((R)-(1,1'-binaphthyl-2,2'-diyl)bis(diphenylphosphine))RuCl2>2NEt3; hydrogen; toluene-4-sulfonic acid; In methanol; toluene;
DOI:10.1021/jo971733d