1-Tert-butyl 3-methyl 2-oxopyrrolidine-1,3-dicarboxylate

Base Information

Chemical Name:1-Tert-butyl 3-methyl 2-oxopyrrolidine-1,3-dicarboxylate
CAS No.:431079-79-7
Molecular Formula:C₁₁H₁₇NO₅
Molecular Weight:243.26
Hs Code.:
DSSTox Substance ID:DTXSID30462697
Nikkaji Number:J1.669.432K
Mol file:431079-79-7.mol

Synonyms:1-tert-butyl 3-methyl 2-oxopyrrolidine-1,3-dicarboxylate;431079-79-7;1-O-tert-butyl 3-O-methyl 2-oxopyrrolidine-1,3-dicarboxylate;1-(TERT-BUTYL) 3-METHYL 2-OXOPYRROLIDINE-1,3-DICARBOXYLATE;SCHEMBL18039817;DTXSID30462697;MFCD16890151;AKOS015855230;AT22439;HE-0736;CS-0141053;FT-0682035;J-505133;1-tert-butyl3-methyl2-oxopyrrolidine-1,3-dicarboxylate

Suppliers and Price of 1-Tert-butyl 3-methyl 2-oxopyrrolidine-1,3-dicarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
1-tert-Butyl 3-methyl 2-oxopyrrolidine-1,3-dicarboxylate >95%
500mg
$ 230.00

Crysdot
1-tert-Butyl3-methyl2-oxopyrrolidine-1,3-dicarboxylate 95+%
1g
$ 287.00

Crysdot
1-tert-Butyl3-methyl2-oxopyrrolidine-1,3-dicarboxylate 95+%
100mg
$ 72.00

Alichem
1-tert-Butyl3-methyl2-oxopyrrolidine-1,3-dicarboxylate
1g
$ 400.00

AK Scientific
1-tert-Butyl3-methyl2-oxopyrrolidine-1,3-dicarboxylate
500mg
$ 360.00

Total 9 raw suppliers

Chemical Property of 1-Tert-butyl 3-methyl 2-oxopyrrolidine-1,3-dicarboxylate

Chemical Property:

Melting Point:65-67 °C
Boiling Point:361.6±35.0 °C(Predicted)
PKA:13.24±0.20(Predicted)
Density:1.209±0.06 g/cm3(Predicted)
Storage Temp.:2-8°C
XLogP3:1.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:243.11067264
Heavy Atom Count:17
Complexity:344

Purity/Quality:

98%min ^*data from raw suppliers

1-tert-Butyl 3-methyl 2-oxopyrrolidine-1,3-dicarboxylate >95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1CCC(C1=O)C(=O)OC

Technology Process of 1-Tert-butyl 3-methyl 2-oxopyrrolidine-1,3-dicarboxylate

There total 3 articles about 1-Tert-butyl 3-methyl 2-oxopyrrolidine-1,3-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 85909-08-6
tert-butyl 2-oxopyrrolidine-1-carboxylate

: 79-22-1
methyl chloroformate

: 431079-79-7
1-(tert-butyl) 3-methyl 2-oxopyrrolidine-1,3-dicarboxylate

Guidance literature:: With lithium hexamethyldisilazane; In tetrahydrofuran; cyclohexane; at -78 ℃;
DOI:10.1021/ol1000654

Reference yield:

: 616-45-5
2-pyrrolidinon

: 24424-99-5
di-tert-butyl dicarbonate

: 79-22-1
methyl chloroformate

: 431079-79-7
1-(tert-butyl) 3-methyl 2-oxopyrrolidine-1,3-dicarboxylate

Guidance literature:: 2-pyrrolidinon; di-tert-butyl dicarbonate; With dmap; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; at 20 ℃; for 24h;

With lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃; for 0.5h;

methyl chloroformate; In tetrahydrofuran; at -78 - 20 ℃;

Reference yield:

: 616-45-5
2-pyrrolidinon

: 24424-99-5
di-tert-butyl dicarbonate

: 616-38-6
carbonic acid dimethyl ester

: 431079-79-7
1-(tert-butyl) 3-methyl 2-oxopyrrolidine-1,3-dicarboxylate

Guidance literature:: 2-pyrrolidinon; di-tert-butyl dicarbonate; With dmap; In dichloromethane; at 20 ℃;

carbonic acid dimethyl ester; With lithium hexamethyldisilazane; In dichloromethane; at -78 ℃;
DOI:10.1039/b802447b