1-<(2-benzoxy-1-(benzoxymethyl)ethoxy)methyl>-1,2,4-triazole-3-carboxylic acid methyl ester

Base Information

• Chemical Name: 1-<(2-benzoxy-1-(benzoxymethyl)ethoxy)methyl>-1,2,4-triazole-3-carboxylic acid methyl ester
• CAS No.: 90330-23-7
• Molecular Formula: C₂₂H₂₅N₃O₅
• Molecular Weight: 411.458
• Mol file: 90330-23-7.mol

Synonyms:1-<(2-benzoxy-1-(benzoxymethyl)ethoxy)methyl>-1,2,4-triazole-3-carboxylic acid methyl ester

Chemical Property of 1-<(2-benzoxy-1-(benzoxymethyl)ethoxy)methyl>-1,2,4-triazole-3-carboxylic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 1-<(2-benzoxy-1-(benzoxymethyl)ethoxy)methyl>-1,2,4-triazole-3-carboxylic acid methyl ester

There total 1 articles about 1-<(2-benzoxy-1-(benzoxymethyl)ethoxy)methyl>-1,2,4-triazole-3-carboxylic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,3-dibenzyloxy-2-(chloromethoxy)propane (74564-16-2) + methyl 1H-1,2,4-triazole-3-carboxylate (4928-88-5) → 1-<(2-benzoxy-1-(benzoxymethyl)ethoxy)methyl>-1,2,4-triazole-3-carboxylic acid methyl ester (90330-23-7) + 1-<(2-benzoxy-1-(benzoxymethyl)ethoxy)methyl>-1,2,4-triazole-5-carboxylic acid methyl ester (90330-24-8)

Guidance literature:

Yield given. Multistep reaction. Yields of byproduct given; 1) trimethylsilylation 2) MeCN, room temperature, 2 days;

DOI:10.1016/S0040-4039(00)99951-9

Reference yield: 84.0%

1-<(2-benzoxy-1-(benzoxymethyl)ethoxy)methyl>-1,2,4-triazole-3-carboxylic acid methyl ester (90330-23-7) → 1-(2-Benzyloxy-1-benzyloxymethyl-ethoxymethyl)-1H-[1,2,4]triazole-3-carboxylic acid amide (90330-25-9)

Guidance literature:

With ammonia; In methanol; for 24h; Ambient temperature;

DOI:10.1016/S0040-4039(00)99951-9

upstream raw materials:

1,3-dibenzyloxy-2-(chloromethoxy)propane

methyl 1H-1,2,4-triazole-3-carboxylate

Downstream raw materials:

1-(2-Benzyloxy-1-benzyloxymethyl-ethoxymethyl)-1H-[1,2,4]triazole-3-carboxylic acid amide