3-[(2-Ethoxyphenoxy)methyl]piperidine

Base Information

Chemical Name:3-[(2-Ethoxyphenoxy)methyl]piperidine
CAS No.:104778-54-3
Molecular Formula:C14H21 N O2
Molecular Weight:235.322
Hs Code.:2933399090
DSSTox Substance ID:DTXSID80909204
ChEMBL ID:CHEMBL73320
Mol file:104778-54-3.mol

Synonyms:3-[(2-ethoxyphenoxy)methyl]piperidine;104778-54-3;3-((2-Ethoxyphenoxy)methyl)piperidine;BRN 1461342;Piperidine, 3-((2-ethoxyphenoxy)methyl)-;CHEMBL73320;SCHEMBL3324885;DTXSID80909204;AKOS000170041;LS-115512;A1-41685

Suppliers and Price of 3-[(2-Ethoxyphenoxy)methyl]piperidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
3-[(2-Ethoxyphenoxy)methyl]piperidine
500mg
$ 205.00

Crysdot
3-((2-Ethoxyphenoxy)methyl)piperidine 97%
5g
$ 648.00

American Custom Chemicals Corporation
3-[(2-ETHOXYPHENOXY)METHYL]PIPERIDINE 95.00%
500MG
$ 802.73

AK Scientific
3-[(2-Ethoxyphenoxy)methyl]piperidine
500mg
$ 326.00

Total 3 raw suppliers

Chemical Property of 3-[(2-Ethoxyphenoxy)methyl]piperidine

Chemical Property:

Vapor Pressure:9.49E-05mmHg at 25°C
Boiling Point:339°C at 760 mmHg
Flash Point:142°C
PSA：30.49000
Density:1.012g/cm³
LogP:2.79250
XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:235.157228913
Heavy Atom Count:17
Complexity:210

Purity/Quality:

98%min ^*data from raw suppliers

3-[(2-Ethoxyphenoxy)methyl]piperidine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC1=CC=CC=C1OCC2CCCNC2

Technology Process of 3-[(2-Ethoxyphenoxy)methyl]piperidine

There total 6 articles about 3-[(2-Ethoxyphenoxy)methyl]piperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 104778-59-8
1-benzyl-3-<(2-ethoxyphenoxy)methyl>piperidine

: 104778-54-3
3-<(2-ethoxyphenoxy)methyl>piperidine

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; at 50 ℃; for 5h;
DOI:10.1021/jm00384a040

Reference yield:

: 614-18-6
3-pyridinecarboxylic acid ethyl ester

: 104778-54-3
3-<(2-ethoxyphenoxy)methyl>piperidine

Guidance literature:: Multi-step reaction with 5 steps

1: 1.) Na 2.) H₂ / 2.) 10percent Pd/C / 1.) EtOH, 2.) EtOH, RT, atm. pressure, 6 h

2: 3.2 g / K₂CO₃ / acetone / 24 h / Ambient temperature

3: 1.4 g / SOCl₂, HCl / CHCl₃ / 1.5 h / Heating

4: ethanol / 30 h / 100 °C

5: 0.7 g / H₂ / 10percent Pd/C / ethanol / 5 h / 50 °C

With hydrogenchloride; thionyl chloride; hydrogen; sodium; potassium carbonate; palladium on activated charcoal; In ethanol; chloroform; acetone;
DOI:10.1021/jm00384a040

Reference yield:

: 4606-65-9
3-(hydroxymethy)piperidine

: 104778-54-3
3-<(2-ethoxyphenoxy)methyl>piperidine

Guidance literature:: Multi-step reaction with 4 steps

1: 3.2 g / K₂CO₃ / acetone / 24 h / Ambient temperature

2: 1.4 g / SOCl₂, HCl / CHCl₃ / 1.5 h / Heating

3: ethanol / 30 h / 100 °C

4: 0.7 g / H₂ / 10percent Pd/C / ethanol / 5 h / 50 °C

With hydrogenchloride; thionyl chloride; hydrogen; potassium carbonate; palladium on activated charcoal; In ethanol; chloroform; acetone;
DOI:10.1021/jm00384a040