Carbonic acid 4-fluoro-2-(5-{2-[2-(methoxycarbonyl-methyl-amino)-phenyl]-acetyl}-2,2,4-trimethyl-1,2-dihydro-quinolin-6-yl)-phenyl ester methyl ester

Base Information

Chemical Name:Carbonic acid 4-fluoro-2-(5-{2-[2-(methoxycarbonyl-methyl-amino)-phenyl]-acetyl}-2,2,4-trimethyl-1,2-dihydro-quinolin-6-yl)-phenyl ester methyl ester
CAS No.:1026870-16-5
Molecular Formula:C₃₁H₃₁FN₂O₆
Molecular Weight:546.595
Hs Code.:

Carbonic acid 4-fluoro-2-(5-{2-[2-(methoxycarbonyl-methyl-amino)-phenyl]-acetyl}-2,2,4-trimethyl-1,2-dihydro-quinolin-6-yl)-phenyl ester methyl ester

Synonyms:Carbonic acid 4-fluoro-2-(5-{2-[2-(methoxycarbonyl-methyl-amino)-phenyl]-acetyl}-2,2,4-trimethyl-1,2-dihydro-quinolin-6-yl)-phenyl ester methyl ester

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Chemical Property of Carbonic acid 4-fluoro-2-(5-{2-[2-(methoxycarbonyl-methyl-amino)-phenyl]-acetyl}-2,2,4-trimethyl-1,2-dihydro-quinolin-6-yl)-phenyl ester methyl ester

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Technology Process of Carbonic acid 4-fluoro-2-(5-{2-[2-(methoxycarbonyl-methyl-amino)-phenyl]-acetyl}-2,2,4-trimethyl-1,2-dihydro-quinolin-6-yl)-phenyl ester methyl ester

There total 3 articles about Carbonic acid 4-fluoro-2-(5-{2-[2-(methoxycarbonyl-methyl-amino)-phenyl]-acetyl}-2,2,4-trimethyl-1,2-dihydro-quinolin-6-yl)-phenyl ester methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 611-21-2
N,2-dimethylaniline

: 1026870-16-5
Carbonic acid 4-fluoro-2-(5-{2-[2-(methoxycarbonyl-methyl-amino)-phenyl]-acetyl}-2,2,4-trimethyl-1,2-dihydro-quinolin-6-yl)-phenyl ester methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-BuLi; CO₂ (gas) / tetrahydrofuran; hexane / -78 - -15 °C

1.2: n-BuLi / tetrahydrofuran / -78 - 15 °C

1.3: 0.10 g / tetrahydrofuran; hexane / -78 - -40 °C

2.1: pyridine / CH₂Cl₂ / 0.17 h

With pyridine; n-butyllithium; carbon dioxide; In tetrahydrofuran; hexane; dichloromethane;
DOI:10.1021/jm020477g

Reference yield:

: 179895-41-1
9-Fluoro-2,2,4-trimethyl-1,2-dihydro-6-oxa-1-aza-chrysen-5-one

: 1026870-16-5
Carbonic acid 4-fluoro-2-(5-{2-[2-(methoxycarbonyl-methyl-amino)-phenyl]-acetyl}-2,2,4-trimethyl-1,2-dihydro-quinolin-6-yl)-phenyl ester methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-BuLi; CO₂ (gas) / tetrahydrofuran; hexane / -78 - -15 °C

1.2: n-BuLi / tetrahydrofuran / -78 - 15 °C

1.3: 0.10 g / tetrahydrofuran; hexane / -78 - -40 °C

2.1: pyridine / CH₂Cl₂ / 0.17 h

With pyridine; n-butyllithium; carbon dioxide; In tetrahydrofuran; hexane; dichloromethane;
DOI:10.1021/jm020477g