3-Ethyl-3-(3-hydroxyphenyl)-1-propylpiperidine hydrobromide

Base Information

Chemical Name:3-Ethyl-3-(3-hydroxyphenyl)-1-propylpiperidine hydrobromide
CAS No.:126088-59-3
Molecular Formula:BrH*C₁₆H₂₅NO
Molecular Weight:328.293
Hs Code.:
DSSTox Substance ID:DTXSID90925399
Mol file:126088-59-3.mol

Synonyms:3-Ethyl-3-(3-hydroxyphenyl)-1-propylpiperidine hydrobromide;126088-59-3;Phenol, 3-(3-ethyl-1-propyl-3-piperidinyl)-, hydrobromide;C16H25N.O.BrH;C16-H25-N.O.Br-H;DTXSID90925399;LS-104653;3-(3-Ethyl-1-propylpiperidin-3-yl)phenol--hydrogen bromide (1/1)

Suppliers and Price of 3-Ethyl-3-(3-hydroxyphenyl)-1-propylpiperidine hydrobromide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
3-ETHYL-3-(3-HYDROXYPHENYL)-1-PROPYLPIPERIDINE HYDROBROMIDE 95.00%
5MG
$ 499.00

Total 2 raw suppliers

Chemical Property of 3-Ethyl-3-(3-hydroxyphenyl)-1-propylpiperidine hydrobromide

Chemical Property:

Vapor Pressure:6.27E-06mmHg at 25°C
Boiling Point:367.8°C at 760 mmHg
Flash Point:164°C
PSA：23.47000
LogP:4.44180
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:327.11978
Heavy Atom Count:19
Complexity:256

Purity/Quality:

99% ^*data from raw suppliers

3-ETHYL-3-(3-HYDROXYPHENYL)-1-PROPYLPIPERIDINE HYDROBROMIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCN1CCCC(C1)(CC)C2=CC(=CC=C2)O.Br

Technology Process of 3-Ethyl-3-(3-hydroxyphenyl)-1-propylpiperidine hydrobromide

There total 6 articles about 3-Ethyl-3-(3-hydroxyphenyl)-1-propylpiperidine hydrobromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 126088-46-8
3-ethyl-3-(3-methoxyphenyl)-1-propylpiperidine

: 126088-59-3
3-(3-Ethyl-1-propyl-piperidin-3-yl)-phenol; hydrobromide

Guidance literature:: With hydrogen bromide; for 2h; Heating;
DOI:10.1002/jhet.5570260441

Reference yield:

: 675-20-7
piperidin-2-one

: 126088-59-3
3-(3-Ethyl-1-propyl-piperidin-3-yl)-phenol; hydrobromide

Guidance literature:: Multi-step reaction with 6 steps

1: 85 percent / potassium hydroxide / dimethylsulfoxide / 2 h / Ambient temperature

2: 86 percent / lithium diisopropylamide / tetrahydrofuran; hexane / 2 h / Ambient temperature

3: 51 percent / iodine / methanol / 3 h / Heating; further reagent, further solvent

4: 93 percent / lithium diisopropylamide / tetrahydrofuran; hexane / 2 h / Ambient temperature

5: 88 percent / lithium aluminum hydride / tetrahydrofuran / 4 h / Heating

6: 79 percent / aq. 48percent hydrobromic acid / 2 h / Heating

With potassium hydroxide; lithium aluminium tetrahydride; hydrogen bromide; iodine; lithium diisopropyl amide; In tetrahydrofuran; methanol; hexane; dimethyl sulfoxide;
DOI:10.1002/jhet.5570260441

Reference yield:

: 15865-19-7
1-propyl-2-piperidinone

: 126088-59-3
3-(3-Ethyl-1-propyl-piperidin-3-yl)-phenol; hydrobromide

Guidance literature:: Multi-step reaction with 5 steps

1: 86 percent / lithium diisopropylamide / tetrahydrofuran; hexane / 2 h / Ambient temperature

2: 51 percent / iodine / methanol / 3 h / Heating; further reagent, further solvent

3: 93 percent / lithium diisopropylamide / tetrahydrofuran; hexane / 2 h / Ambient temperature

4: 88 percent / lithium aluminum hydride / tetrahydrofuran / 4 h / Heating

5: 79 percent / aq. 48percent hydrobromic acid / 2 h / Heating

With lithium aluminium tetrahydride; hydrogen bromide; iodine; lithium diisopropyl amide; In tetrahydrofuran; methanol; hexane;
DOI:10.1002/jhet.5570260441