N-[2-(3-ethoxy-3-oxopropyl)-5-(phenoxymethyl)benzoyl]-Smethyl-S-phenylsulfoximine

Base Information

Chemical Name:N-[2-(3-ethoxy-3-oxopropyl)-5-(phenoxymethyl)benzoyl]-Smethyl-S-phenylsulfoximine
CAS No.:1616088-57-3
Molecular Formula:C₂₆H₂₇NO₅S
Molecular Weight:465.57
Hs Code.:

Synonyms:N-[2-(3-ethoxy-3-oxopropyl)-5-(phenoxymethyl)benzoyl]-Smethyl-S-phenylsulfoximine

Suppliers and Price of N-[2-(3-ethoxy-3-oxopropyl)-5-(phenoxymethyl)benzoyl]-Smethyl-S-phenylsulfoximine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-[2-(3-ethoxy-3-oxopropyl)-5-(phenoxymethyl)benzoyl]-Smethyl-S-phenylsulfoximine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-[2-(3-ethoxy-3-oxopropyl)-5-(phenoxymethyl)benzoyl]-Smethyl-S-phenylsulfoximine

There total 6 articles about N-[2-(3-ethoxy-3-oxopropyl)-5-(phenoxymethyl)benzoyl]-Smethyl-S-phenylsulfoximine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 1616087-99-0
C₂₁H₁₉NO₃S

: 140-88-5,9003-32-1
ethyl acrylate

: 1616088-57-3
N-[2-(3-ethoxy-3-oxopropyl)-5-(phenoxymethyl)benzoyl]-Smethyl-S-phenylsulfoximine

Guidance literature:: C₂₁H₁₉NO₃S; ethyl acrylate; With silver hexafluoroantimonate; [ruthenium(II)(η⁶-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]₂; copper(II) acetate hydrate; In 1,2-dichloro-ethane; at 120 ℃; for 24h; Inert atmosphere; Glovebox; Schlenk technique;

With sodium tetrahydroborate; nickel(II) chloride hexahydrate; In tetrahydrofuran; methanol; at 0 ℃; regioselective reaction; Inert atmosphere; Schlenk technique;
DOI:10.1021/jo5008465

Reference yield:

: 1616087-99-0
C₂₁H₁₉NO₃S

: 140-88-5,9003-32-1
ethyl acrylate

: 1616088-56-2
C₂₆H₂₅NO₅S

: 1616088-57-3
N-[2-(3-ethoxy-3-oxopropyl)-5-(phenoxymethyl)benzoyl]-Smethyl-S-phenylsulfoximine

Guidance literature:: With silver hexafluoroantimonate; [ruthenium(II)(η⁶-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]₂; copper(II) acetate hydrate; In 1,2-dichloro-ethane; at 120 ℃; for 24h; Overall yield = 66 %; Overall yield = 2.1 g; regioselective reaction; Inert atmosphere; Glovebox; Schlenk technique;
DOI:10.1021/jo5008465

Reference yield:

: 1193-82-4
racemic methyl phenyl sulfoxide

: 1616088-57-3
N-[2-(3-ethoxy-3-oxopropyl)-5-(phenoxymethyl)benzoyl]-Smethyl-S-phenylsulfoximine

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium azide; sulfuric acid / chloroform / Schlenk technique

2.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap / dichloromethane / 12 h / 0 - 20 °C / Inert atmosphere; Schlenk technique

3.1: [ruthenium(II)(η⁶-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]₂; copper(II) acetate hydrate; silver hexafluoroantimonate / 1,2-dichloro-ethane / 24 h / 120 °C / Inert atmosphere; Glovebox; Schlenk technique

3.2: 0 °C / Inert atmosphere; Schlenk technique

With dmap; silver hexafluoroantimonate; sodium azide; [ruthenium(II)(η⁶-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]₂; copper(II) acetate hydrate; sulfuric acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; chloroform; 1,2-dichloro-ethane;
DOI:10.1021/jo5008465