N⁶-cyclohexyl-2-fluoroadenine

Base Information

• Chemical Name: N⁶-cyclohexyl-2-fluoroadenine
• CAS No.: 852231-88-0
• Molecular Formula: C₁₁H₁₄FN₅
• Molecular Weight: 235.264
• Mol file: 852231-88-0.mol

Synonyms:N⁶-cyclohexyl-2-fluoroadenine

Chemical Property of N⁶-cyclohexyl-2-fluoroadenine

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of N⁶-cyclohexyl-2-fluoroadenine

There total 1 articles about N⁶-cyclohexyl-2-fluoroadenine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

cyclohexylamine (108-91-8,157973-60-9) + 6-chloro-2-fluoropurine (1651-29-2) → N6-cyclohexyl-2-fluoroadenine (852231-88-0)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In butan-1-ol; at 80 ℃; for 12h;

DOI:10.1021/ja037390k

Reference yield: 36.4%

N-(4-aminophenyl)-N'-propargylpiperazine + N6-cyclohexyl-2-fluoroadenine (852231-88-0) → N6-cyclohexyl-2-(4-(4-propargylpiperazin-1-yl)-N-anilinyl)adenine

Guidance literature:

In ethanol; at 130 ℃; for 5h; Inert atmosphere;

DOI:10.1002/cmdc.201200493

Reference yield:

4-morpholino-4-yl-phenylamine (2524-67-6,86759-37-7) + N6-cyclohexyl-2-fluoroadenine (852231-88-0) → Reversine

Guidance literature:

In ethanol; at 75 ℃; for 24h;

DOI:10.1021/ja037390k

upstream raw materials:

cyclohexylamine

6-chloro-2-fluoropurine

Downstream raw materials:

MRS 3767