α-(N-benzoylamino)methyltriphenylphosphonium bromide

Base Information

• Chemical Name: α-(N-benzoylamino)methyltriphenylphosphonium bromide
• CAS No.: 28387-29-3
• Molecular Formula: Br*C₂₆H₂₃NOP
• Molecular Weight: 476.352
• Mol file: 28387-29-3.mol

Synonyms:α-(N-benzoylamino)methyltriphenylphosphonium bromide

Chemical Property of α-(N-benzoylamino)methyltriphenylphosphonium bromide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of α-(N-benzoylamino)methyltriphenylphosphonium bromide

There total 8 articles about α-(N-benzoylamino)methyltriphenylphosphonium bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.1%

methyl N-benzoyl-α-triphenylphosphonioglycinate bromide → C20H18N2O6 (498572-96-6) + Methyltriphenylphosphonium bromide (1779-49-3) + α-(N-benzoylamino)methyltriphenylphosphonium bromide (28387-29-3)

Guidance literature:

methyl N-benzoyl-α-triphenylphosphonioglycinate bromide; at 25 ℃; for 1h; under 1 - 2 Torr;

With triphenylphosphine hydrobromide; triphenylphosphine; at 110 - 120 ℃; for 1h;

DOI:10.1016/j.tca.2010.08.017

Reference yield: 71.5%

methyl N-benzoyl-α-triphenylphosphonioglycinate bromide → Methyltriphenylphosphonium bromide (1779-49-3) + α-(N-benzoylamino)methyltriphenylphosphonium bromide (28387-29-3)

Guidance literature:

With triphenylphosphine hydrobromide; triphenylphosphine; at 115 ℃; for 1.5h; under 1 - 2 Torr;

DOI:10.1016/j.tca.2010.08.017

Reference yield:

N-(hydroxymethyl)benzamide (6282-02-6) → α-(N-benzoylamino)methyltriphenylphosphonium bromide (28387-29-3)

Guidance literature:

Multi-step reaction with 2 steps

1: PBr₅

With phosphorus pentabromide;

upstream raw materials:

({[1-Methoxy-1-phenyl-meth-(Z)-ylidene]-amino}-methyl)-triphenyl-phosphonium; bromide

N-bromomethyl-benzamide

triphenylphosphine

N-(hydroxymethyl)benzamide