Technology Process of 2-[(2-benzhydryloxy-ethyl)-methyl-amino]-ethanol
There total 4 articles about 2-[(2-benzhydryloxy-ethyl)-methyl-amino]-ethanol which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
camphor-10-sulfonic acid;
In
methanol; dichloromethane;
at 0 ℃;
for 1.5h;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: tetrachloromethane; triphenylphosphine; sodium hydrogencarbonate / 12 h / Reflux
2.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 0 °C
2.2: 12 h / 20 °C
3.1: camphor-10-sulfonic acid / dichloromethane; methanol / 1.5 h / 0 °C
With
tetrachloromethane; camphor-10-sulfonic acid; sodium hydride; sodium hydrogencarbonate; triphenylphosphine;
In
methanol; dichloromethane; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: 1H-imidazole / dichloromethane / 0.08 h / 0 °C
1.2: 0.5 h
2.1: tetrachloromethane; triphenylphosphine; sodium hydrogencarbonate / 12 h / Reflux
3.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 0 °C
3.2: 12 h / 20 °C
4.1: camphor-10-sulfonic acid / dichloromethane; methanol / 1.5 h / 0 °C
With
1H-imidazole; tetrachloromethane; camphor-10-sulfonic acid; sodium hydride; sodium hydrogencarbonate; triphenylphosphine;
In
methanol; dichloromethane; N,N-dimethyl-formamide;
