Xi:Irritant;
105-59-9Relevant articles and documents
Synthesis of 2-(dimethylamino)ethanol by the hydrogenolysis of tris(2-hydroxyethyl)amine
Kiyoura, Tadamitsu,Muraishi, Teruo
, p. 1829 - 1829 (1996)
A new reaction for the selective hydrogenolysis of tris(2-hydroxyethyl)amine into 2-(dimethylamino)ethanol by molecular hydrogen over metallic palladium catalyst is disclosed.
RANEY nickel-catalyzed reductive N-methylation of amines with paraformaldehyde: Theoretical and experimental study
Ge, Xin,Luo, Chenxi,Qian, Chao,Yu, Zhiping,Chen, Xinzhi
, p. 43195 - 43203 (2015/02/19)
RANEY Ni-catalyzed reductive N-methylation of amines with paraformaldehyde has been investigated. This reaction proceeds in high yield with water as a byproduct. RANEY Ni can be easily recovered and reused with a slight decrease of the yield. Using density functional theory (DFT), the mechanism of RANEY Ni-catalyzed reductive N-methylation is discussed in detail. The reaction pathway involves the addition of amine with formaldehyde, dehydration to form the imine and hydrogenation. In the transition state of hemiaminal dehydration, the C-O bond cleavage of the aromatic amine is more difficult than that of the aliphatic amine. For the aromatic amine, a higher energy barrier must be overcome, which results in a relatively low yield. After addition of amine with formaldehyde and dehydration, imine is obtained and preferred to adsorb on the bridge site of the Ni(111) surface. The preferential pathways of imine hydrogenation involve the pre-adsorbed hydrogen atom attacking the nitrogen atom of the imine. The energy barrier of hydrogenation is much lower than that of addition and dehydration. Thus, the hydrogenation of imine is a relatively rapid reaction step. In the reductive N-methylation of secondary amine, the possible dehydration pathway is different from the one of the primary amine. In the dehydration of the secondary amine, the intermediate hemiaminal is initially adsorbed on the bridge site of the Ni(111) surface, then undergoes C-O bond cleavage, and eventually the hydroxyl is located in the bridge site. With the final hydrogenation, the product is obtained by adsorption on the top site of the Ni(111) surface.
Additives and products including oligoesters
-
, (2008/06/13)
The present invention relates to oligoesters and their use or the creation of additives. Oligoester containing additives and/or oligoesters themselves may be used for formulating pharmaceutical preparations, cosmetics or personal care products such as shampoos and conditioners. These oligoesters are particularly useful for the creation of multi-purpose additives that can impart conditioning, long substantivity and/or UV protection. Individual oligoesters and oligoester mixtures are described.
